281652-58-2

Basic information

• Product Name: 2-Chloro-5-iodo-benzoyl chloride
• Synonyms: 2-Chloro-5-iodo-benzoyl chloride
• CAS NO: 281652-58-2
• Molecular Formula: C₇H₃Cl₂IO
• Molecular Weight: 300.90859
• Mol File: 281652-58-2.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 309.9±27.0 °C(Predicted)
• Appearance: /
• Density: 2.007±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Chloro-5-iodo-benzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-iodo-benzoyl chloride(281652-58-2)
• EPA Substance Registry System: 2-Chloro-5-iodo-benzoyl chloride(281652-58-2)

Safety Data

• Hazardous Substances Data: 281652-58-2(Hazardous Substances Data)

Usage

General Description

2-Chloro-5-iodo-benzoyl chloride, also known as 2-Chloro-5-iodobenzoyl chloride, is a chemical compound with the molecular formula C7H3ClIO. It is a versatile building block used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is a white to off-white crystalline solid that is highly reactive and must be handled with care. 2-Chloro-5-iodo-benzoyl chloride has a wide range of applications in organic synthesis, including as a reagent for acylation reactions and as a precursor for the preparation of various benzoyl halides and aryl esters. It is also used in the manufacture of dyes and pigments and as a starting material for the production of specialty chemicals.

Upstream product

• 79-37-8 oxalyl dichloride 
• 19094-56-5 2-chloro-5-iodobenzoic acid 

Downstream Products

• 1103738-26-6 (2-chloro-5-iodo-phenyl)-(4-ethoxyphenyl)methanone 
• 1132832-77-9 (2-chloro-5-iodo-phenyl)-[5-(6-fluoro-pyridin-3-yl)-thiophen-2-yl]-methanone 
• 1049811-36-0 (2-Chloro-5-iodo-benzyl)-cyclopentyl-amine 
• 1459754-39-2 (2-chloro-5-iodophenyl)(4-methoxyphenyl)methanone 

Relevant articles and documents

An anti-diabetic drug intermediate and preparation method thereof

The present invention discloses an antidiabetic drug intermediate and a method for preparing it, comprising: the 2-chloro-5-iodobenzoic acid first reacted with a halogenated reagent, the reaction was complete and then added 2-fluorophene and Lewis acid fo

GLUCOPYRANOSE DERIVATIVES USEFUL AS SGLT2 INHIBITORS

The present invention is directed to glucopyranose derivatives of formula (I), pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by SGLT2 activity. More particularly, the compounds of the present invention are useful in the treatment of for example, Type II diabetes mellitus, Syndrome X, and complications and symptoms associated with said disorders.

Preparation method of empagliflozin intermediate impurity

The invention relates to the field of drug synthesis, in particular to a preparation method of an empagliflozin intermediate impurity (S)-3-(2-(2-chloro-5-iodobenzyl) phenoxy)tetrahydrofuran. The invention discloses a preparation method of an empagliflozi