2069942-68-1

Basic information

• Product Name: EMpagliflozin iMpurity 10
• Synonyms: EMpagliflozin iMpurity 10;(3R,4S,5R,6R)-6-(acetoxymethyl)-2-(4-chloro-3-(4-(((S)- tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-2-methoxytetrahydro-2H -pyran-3,4,5-triyl triacetate
• CAS NO: 2069942-68-1
• Molecular Formula: C32H37ClO12
• Molecular Weight: 649.08
• EINECS: -0
• Mol File: 2069942-68-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: EMpagliflozin iMpurity 10(CAS DataBase Reference)
• NIST Chemistry Reference: EMpagliflozin iMpurity 10(2069942-68-1)
• EPA Substance Registry System: EMpagliflozin iMpurity 10(2069942-68-1)

Safety Data

• Hazardous Substances Data: 2069942-68-1(Hazardous Substances Data)

Upstream product

• 90-80-2 D-Glucono-1,5-lactone 
• 32469-28-6 (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one 
• 915095-96-4 methyl-1-C-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucopyranoside 
• 108-24-7 acetic anhydride 
• 915095-86-2 (2-chloro-5-iodophenyl)(4-fluorophenyl)methanone 
• 281652-58-2 2-chloro-5-iodobenzoylchloride 
• 19094-56-5 2-chloro-5-iodobenzoic acid 
• 1279691-36-9 (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 915095-94-2 (3S)-3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran 
• 915095-87-3 (S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone 

Downstream Products

• 915095-99-7 (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate 
• 915095-99-7 C₃₁H₃₅ClO₁₁ 

Relevant articles and documents

Industrial preparation method for empagliflozin

The invention discloses an industrial preparation method for empagliflozin. Specifically, the invention relates to a preparation method for empagliflozin as shown in formula as defined in the specification, i.e., (1S)-1,5-dehydro-1-(4-chloro-3{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}pheyl)-D-glucitol, and an intermediate prepared by using the method. The preparation method for empagliflozin in the invention is stable in process, good in reproducibility and suitable for large-scale production.