28178-96-3

Upstream product

• 90-15-3 α-naphthol 
• 2876-13-3 N-benzylpyridinium chloride 
• 51010-48-1 1-methoxy-4-benzylnaphthalene 
• 100-44-7 benzyl chloride 
• 24776-44-1 4-benzoyl-1-naphthol 
• 71-43-2 benzene 
• 7732-18-5 water 
• 93654-98-9 phenyl acetic acid naphthalen-1-yl ester 
• 100-39-0 benzyl bromide 
• 98-88-4 benzoyl chloride 
• 2607-25-2 1-iodo-4-methoxynaphthalene 
• 607-58-9 1-(phenylmethoxy)naphthalene 

Downstream Products

• 51010-48-1 1-methoxy-4-benzylnaphthalene 
• 108054-95-1 2-Hydroxy-4-[1-phenyl-meth-(E)-ylidene]-4H-naphthalen-1-one 
• 1533457-59-8 4-benzylnaphthalen-1-yl pivalate 

Relevant academic research and scientific papers

Microwave-Assisted solid-liquid phase alkylation of naphthols

The microwave promoted alkylation of 1- and 2-naphthols with benzyl, butyl, ethyl and isopropyl halides in the presence of an alkali carbonate may result in O- and C-Alkylated products. The alkylations were O-selective in the presence of K2CO3 in acetonitrile as the solvent and in the absence of phase transfer catalyst. The alkylations utilizing butyl and ethyl halides were also O-selective in solventless accomplishment and in the presence of triethylbenzylammonium chloride.

Photo-Fries reaction in water made selective with a capsule

The water soluble capsule formed by a deep cavity cavitand with eight carboxylic acid groups controls product distribution during photo-Fries rearrangement of naphthyl esters in water by restricting the mobility of primary singlet radical pair. The Royal Society of Chemistry.

One step hair coloring compositions using salts

A hair coloring composition comprising the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an amino phenol, a naphthol, a polyhydric phenol, a catechol and mixtures thereof; wherein the composition comprising one or more oxidative hair coloring agents further comprises al least one water soluble carbonate releasing salts; and optionally a water soluble ammonium salt, is described.

Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents.

A new series of 1,2-naphthoquinone derivatives was synthesized by various synthetic methods and evaluated for their ability to inhibit protein tyrosine phosphatase 1B (PTP1B). 1,2-Naphthoquinone derivatives with substituent at R(4) position showed submicromolar inhibitory activity, and compound 24 demonstrated 10- to 60-fold selectivity against the tested phosphatases. Also, several 4-aryl-1,2-naphthoquinone derivatives with substituents at R(3), R(6), R(7), or/and R(8) showed submicromolar inhibitory activity and good plasma stability.

Mediation of photochemical reactions of 1-naphthyl phenylacylates by polyolefin films. A 'radical clock' to measure rates of radical-pair cage recombinations in 'viscous space'

The fates of phenylacyl/1-naphthoxy singlet radical pairs generated upon irradiation of 1-naphthyl phenylacetate (1a) and 1-naphthyl 2-phenylpropanoate (1b) in three unstretched and stretched polyethylene films and isotactic and syndiotactic polypropylene films have been investigated. From dynamic fluorescence measurements the primary locus of reactions by 1 is within amorphous regions of the films. The reaction cages afforded by these media inhibit escape of the radical pairs and mediate their reorientational motions leading to photo-Fries and related products. In essence, the cages act as stiff-walled templates. In addition, a method is described to measure the rate constants for the singlet radical pairs. Thus, the rate constants (leading to the keto precursors) of the 2-phenylacyl-1-naphthols from the radical pairs of 1 (> 108 s-1) are >6 times the rate constants for the 4-isomers. Film stretching increases this selectivity but there is no obvious correlation between the rate of the in-cage radical pair recombinations and macroscopic polymer, properties such as degree of crystallinity and frequency of branched chains. By contrast, formation of (the keto precursors of) 2-benzylic-1-naphthols (from in-cage recombinations after phenylacyl decarbonylation) is slower than for the 4-benzyl-1-naphthols. (C) 2000 Elsevier Science Ltd.

Process for the two-stage oxidation dyeing of keratin fibers with a manganese complex or salt and a 4-substituted 1-naphthol, and dyeing kit

A process for the two-stage oxidation dyeing of keratin fibers by applying to the keratin fibers: in a first stage, at least one composition A containing at least one manganese salt and/or a manganese complex, in a second stage, at least one composition B having a pH of greater than or equal to 6, and resulting from the extemporaneous mixing of at least one composition B1 containing at least one 4-substituted 1-naphthol and at least one composition B2 containing at least one oxidizing agent, and corresponding multi-compartment dyeing kit.

Structural Influences on the Isomerization of 4-Benzyl- and 4-Allyl-1,2-naphthoquinones to Quinonemethides and their Stereochemistry

The isomerization of 4-benzyl-1,2-naphthoquinones and 4-allyl-1,2-naphthoquinones to quinonemethides has been studied.The steric interaction and extra ? conjugation in the quinonemethide, and acidity of methylene protons of the quinone, are controlling fa