282116-41-0

Upstream product

• 1467720-25-7 C₁₂H₁₇BrO₂ 
• 69287-12-3 5-bromo-1-(4-methoxyphenyl)pentan-1-one 
• 4509-90-4 5-bromovaleroyl chloride 
• 100-66-3 methoxybenzene 
• 1613-51-0 sulfure de pentamethylene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 282116-42-1 3,4,5,6-tetrahydro-2-(4-hydroxyphenyl)-2H-thiopyran 

Relevant academic research and scientific papers

Synthesis and Nrf2 activating ability of thiourea and vinyl sulfoxide derivatives

Thiourea and vinyl sulfoxide derivatives were designed based on the structures of sulforaphane and gallic acid, prepared and tested for HO-1 inducing activity as a measure of Nrf2 activation, and inhibitory effect on NO production as a measure of anti-inf

THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP

A compound of formula (I) in which R is lower alkyl, halogen, optionally substituted heterocyclic group or optionally substituted aryl, R is carboxy, protected carboxy or amidated carboxy, Ar is optionally substituted aryl or optionally substituted heterocyclic group, A is lower alkylene, X is oxa or a single bond, Y is thia, sulfinyl or sulfonyl, Z is methylene, thia, sulfinyl or sulfonyl, m and n are each an integer of 0 to 6, and 1/=m+n/=6, or its salt, which is useful as an inhibitor of matrix metalloproteinases (MMP) or tumor necrosis factor alpha (TNF alpha ).