28218-20-4

Upstream product

• 17530-69-7 3-chloro-5,5-dimethylcyclohex-2-en-1-one 
• 28557-00-8 phenylzinc chloride 
• 119441-89-3 (E)-(2-bromoethenyl)diisopropoxyborane 
• 78-59-1 3,5,5-Trimethylcyclohex-2-en-1-one 
• 100-52-7 benzaldehyde 
• 108162-13-6 Z-styryl n-butyltelluride 
• 78998-88-6 5,5-dimethyl-3-(phenylseleno)-2-cyclohexen-1-one 
• 6783-04-6 (E)-2-(2'-phenylethenyl)-1,3,2-benzodioxaborole 
• 536-74-3 phenylacetylene 
• 6783-05-7 trans-2-phenylvinylboronic acid 
• 92249-36-0 5,5-dimethyl-3-oxocyclohex-1-en-1-yl 4-nitrobenzenesulfonate 
• 126-81-8 dimedone 
• 161670-50-4 7-(α-oxybenzyl)isophorone 

Downstream Products

• 4839-46-7 3,3-Dimethylglutaric acid 
• 65-85-0 benzoic acid 
• 1392779-27-9 C₂₃H₂₆OS 

Relevant academic research and scientific papers

Tandem aldol condensation-Diels-Alder-aromatization sequence of reactions: A new pathway for the synthesis of 2-tetralone derivatives

A series of new polysubstituted derivatives of 2-tetralones possessing two ester groups were synthesized via a tandem aldol condensation-Diels-Alder-aromatization sequence of reactions. All the three steps took place in one pot and in the presence of amin

Handy Protocols using Vinyl Nosylates in Suzuki-Miyaura Cross-Coupling Reactions

Vinyl nosylates derived from 1,3-dicarbonyl compounds could be engaged in Suzuki-Myaura cross coupling reactions with aryl-, vinyl- and methylboronic acids or trifluoborate derivatives at room temperature in the presence of 2mol% of [1,1′-bis(diphenylphosphino)ferrocene]dichloropalladium(II) [PdCl2(dppf)]. One-pot procedures have been set up for practical and efficient nosylation-cross-coupling reactions. Nosylate, as a cheap novel pseudo-halide, gives very stable compounds and is very efficient in Suzuki-Myaura cross coupling reactions (21 examples, 44-99%).

Vinyl nosylates: An ideal partner for palladium-catalyzed cross-coupling reactions

In a hurry to leave! Nosylates act as an excellent leaving group in various palladium-catalyzed cross-couplings, such as Suzuki, Stille, Heck, and Sonogashira reactions (see scheme). Crystalline, stable, and cheap vinyl and aryl nosylates proved better th

A novel and efficient tandem aldol condensation-Diels-Alder reaction pathway for the direct synthesis of dehydrodecaline derivatives

An efficient direct synthesis of dehydrodecaline derivatives is reported via a tandem aldol condensation-Diels-Alder cycloaddition process under Lewis acidic conditions. Addition of dienophile moieties to conjugated dienes, formed in situ from the condens

Suzuki-Miyaura cross-coupling of alkenyl tosylates with alkenyl MIDA boronates

A practical procedure for the palladium-catalysed Suzuki-Miyaura coupling of various alkenyl tosylates with alkenyl MIDA boronates has been developed. Commercially available trans-bromo[N-succinimidyl-bis(triphenylphosphine)] palladium(II) [Pd(PPh3/

Facile solvent-free synthesis and structural elucidation of styrylcyclohex-2-enone derivatives

A remarkably efficient procedure for the synthesis of styrylcyclohex-2- enone derivatives at room temperature is described using a mild reaction medium consisting of lithium perchlorate and N-(trimethylsilyl)diethylamine. Several compounds of this class a

Synthesis of 1,2-diazaphenalenes under microwave

1,2-Diazaphenalenes were prepared by condensation reactions of hydrazine with isophorone derivatives under various conditions: conventional heating in homogeneous solution and microwave activation either in homogeneous solution or in dry media. Microwave

Carbonyl transposition on organoselenium compounds

Carbonyl conjugated vinylic selenides undergo 1,3 and 1,5-carbonyl transposition sequences through organometallic reagents addition reactions followed by acid hydrolysis.

Condensation reactions in water of active methylene compounds with arylaldehydes. One-pot synthesis of flavonols

The condensation reactions of acetophenone, cyclohexanone, isophorone, phenylacetonitrile, p-nitrophenylacetonitrile, (phenylsulfonyl)acetonitrile and indene with benzaldehyde were studied in water heterogeneous phase in the presence and absence of anionic and cationic surfactants such as SLS, CTACl, (CTA)2SO4 and CTAOH. All the reactions occur with excellent yields. The cationic surfactants favour the reaction and the comparison with the corresponding tetrabutylammonium salts show that the micellar catalysis is effective mainly towards the dehydration reaction following that of condensation. Anionic surfactant SLS is inactive. 2'-hydroxychalcones were prepared in aqueous medium in good-excellent yields and the one-pot synthesis of 7- and 3',4'-substituted flavonols was achieved.