2844-19-1

Usage

InChI:InChI=1/C16H16BrN/c1-18(2)16-11-7-14(8-12-16)4-3-13-5-9-15(17)10-6-13/h3-12H,1-2H3/b4-3+

Upstream product

• 7297-51-0 trans-4-(amino)-4'-(bromo)stilbene 
• 74-88-4 methyl iodide 
• 34904-03-5 4-(N,N-dimethylamino)benzyltriphenylphosphonium iodide 
• 1122-91-4 4-bromo-benzaldehyde 
• 51044-13-4 4-bromobenzyl triphenylphosphonium bromide 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 38186-51-5 diethyl (4-bromobenzyl)phosphonate 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 106-38-7 para-bromotoluene 
• 92206-72-9 4-bromobenzylmagnesium bromide 
• 160845-68-1 4-[(Z)-2-(4-bromophenyl)ethenyl]-N,N-dimethylbenzenamine 

Downstream Products

• 122212-93-5 4,4',4''-Tris<4-(dimethylamino)styryl>triphenylmethanol 
• 838-95-9 (E)-N,N-dimethyl-4-styrylbenzenamine 
• 92278-49-4 4-{(E)-2-[4-(N,N-dimethylamino)phenyl]ethenyl}benzenecarbaldehyde 
• 952290-36-7 methyl 13-{[trans-4-(4-dimethylaminostyryl)phenyl]-phenylamino}-deisopropyldehydroabietate 
• 1190376-42-1 (E)-N,N-dimethyl-4-{4-[(trimethylsilyl)ethynyl]styryl}aniline 

Relevant academic research and scientific papers

Rhenium and technetium complexes that bind to amyloid-β plaques

Alzheimer's disease is associated with the presence of insoluble protein deposits in the brain called amyloid plaques. The major constituent of these deposits is aggregated amyloid-β peptide. Technetium-99m complexes that bind to amyloid-β plaques could p

Photophysical Properties of Silyl-Substituted Stilbene Derivatives

The effects of silyl groups on the structural, absorption, fluorescence, and photoisomerization properties of stilbenes were investigated. In comparison to that of the parent stilbene (1), fluorescence quantum yields (Φf) of Me3Si-substituted stilbenes 2–4 and 6 in solution were higher. Derivative 5, in which Me3Si groups are present at all ortho positions of the arene moieties, did not fluoresce at room temperature. The absorption and fluorescence wavelength maxima of Me3SiMe2Si-substituted stilbene 7 occurred at longer wavelengths compared to those of the Me3Si analog 2. The results of theoretical calculations showed that this difference is a consequence of an increase in the HOMO energy of 7 caused by orbital interaction between π-system and the σ(Si–Si) orbital. Stilbene 14, with two Me3Si-C≡C groups at both para positions, had a high Φf (0.95). The calculated transition dipole moment (μ) was well correlated with Φf. Derivative 21, which contains Ph2N and Me3SiC≡C groups exhibited solvatofluorochromism because it possesses a twisted intramolecular charge transfer (TICT) excited state in which the Ph2N group and the aromatic ring are orthogonal.

AMYLOID BINDING AGENTS

There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer?s disease and other related amyloid-based neurodegenerative diseases

Synthesis, spectroscopy, photophysics and thermal behaviour of stilbene-based triarylamines with dehydroabietic acid methyl ester moieties

Novel stilbene-based triarylamines with dehydroabietic acid methyl ester moieties have been synthesised by palladium catalysed C-N coupling reactions. The presence of the bulky dehydroabietic acid group increases solubility, hinders crystallisation and pe

Convenient methods for preparing ?-conjugated linkers as building blocks for modular chemistry

Simple, straightforward and optimized procedures for preparing extended ?-conjugated linkers are described. Either unsubstituted or 4-donor substituted ?-linkers bearing a styryl, biphenyl, phenylethenylphenyl, and phenylethynylphenyl ?-conjugated backbone are functionalized with boronic pinacol esters as well as with terminal acetylene moieties allowing their further use as building blocks in Suzuki-Miyaura or Sonogashira coupling reactions.

π-Extended alkylidenecycloproparenes

Reaction of benzene-1,4-dicarboxaldehyde with anion 6 derived from 1,1-bis(trimethylsilyl)cyclopropa[b]naphthalene 1 gives 4-(methylidene-1H-cyclopropanaphthalenyl)benzaldehyde 7 as a minor product and 1,4-bis(methylidene-1H-cyclopropanaphthalenyl)benzene

Chemical partitioning agents and methods of using same

The present invention is directed to partitioning agents and methods of using same to effectuate separation of a reactant, intermediate product, and/or final product from a reaction mixture while minimizing the need for traditional separation or isolation techniques.

Spectroscopic Correlations between Supermolecules and Molecules. Anatomy of the Ion-Modulated Electronic Properties of the Nitrogen Donor in Monoazacrown-Derived Intrinsic Fluoroionophores

The synthesis, absorption and emission spectra, fluorescence quantum yields, and fluorescence lifetimes of three compound series of trans-4,4′-disubstituted aminostilbenes (1-3) are reported. The chromo-/fluoroionophoric behavior of the monoaza-15-crown-5

Trivalent Boron as an Acceptor in Donor - π - Acceptor-Type Compounds for Single- and Two-Photon Excited Fluorescence

The synthesis, structure, and fluorescence properties of a series of new donor - π - acceptor (D - π - A) type compounds, with a trivalent boron, protected by two mesityl groups, as acceptor, and with various typical donors and different π-conjugated bridges, are reported. All these stable organoboron compounds show intense single-photon excited fluorescence (SPEF) and two-photon excited fluorescence (TPEF) in a wide spectral range from blue to green, with the spectral peak position of the SPEF being basically the same as that of the TPEF. The remarkably strong C-B(mesityl)2 bonding, and the well-conjugated π-system, shown in X-ray crystal structures of two compounds, indicate some charge transfer features of the ground state. Meanwhile, spectral data indicate that the charge transfer from donor to acceptor is greatly enhanced in the excited states. Based on typical structural data and comprehensive spectral data, the following structure - property relationships can be drawn: 1) the moderate arylamino donor can more effectively enhance the SPEF and TPEF intensities than can the strong alkylamino donor; 2) stilbene is a better π-bridge than styrylthiophene for its capability of enhancing and blue-shifting the SPEF and TPEF of the corresponding D - π - A compounds; and 3) when compared to its boron-free precursors and other analogues, -B(mesityl)2 invariably and consistently acts as an effective SPEF and TPEF fluorophore in all this series of organoboron compounds, which may result from its strong π -electron-withdrawing and charge transfer-inducing nature in the ground-state and, more dominantly, in the excited-state. Combining all the above positive structure factors, trans-4′-N,N-diphenylamino-4-dimesitylborylstilbene (compound 3) stands out as the optimized green SPEF and TPEF emitter. This compound exhibits an SPEF quantum yield φ of 0.91 at 522 nm in THF, a TPEF cross-section σ′ that is an order of magnitude larger than that of its boron-free precursor upon excitation by 800 nm femto-second laser pulses, and a two-photon absorption section a of 3.0 × 10-48 cm 4 s. In the blue light region, trans-4′ -N-carbazolyl-4-dimesitylborylstilbene (compound 4) shows significant SPEF and TPEF properties, with φ = 0.79 at 464 nm in THF and a large σ′ value, which is five times that of fluorescein upon excitation by 740 nm femto-second laser pulses.

Electronic Structure and Free-Energy Relationships for Some 4'-Substituted 4-Dimethylamino trans-Stilbenes by U.V. Photoelectron Spectroscopy

A series of 4'-substituted 4-dimethylamino trans-stilbenes 1-5 was investigated by UPS, in connection with conjugated donor-acceptor substituted double bond photochemistry.The measured and assigned spectra indicate a high sensitivity, depending on the changed electronic structure by 4'-substituents of compounds 1-5.Correlation of ionization energies in LFE-relationship with Hammett's ?p-values and other ground state data was proved, demonstrating UPS a powerful tool for substituent effect studies in conjugated double bond systems.