2845-43-4

Basic information

• Product Name: 2-((diethylamino)methyl)-1-phenylprop-2-en-1-one
• Synonyms: 2-((diethylamino)methyl)-1-phenylprop-2-en-1-one
• CAS NO: 2845-43-4
• Molecular Weight: 217.311
• Mol File: 2845-43-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-((diethylamino)methyl)-1-phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((diethylamino)methyl)-1-phenylprop-2-en-1-one(2845-43-4)
• EPA Substance Registry System: 2-((diethylamino)methyl)-1-phenylprop-2-en-1-one(2845-43-4)

Safety Data

• Hazardous Substances Data: 2845-43-4(Hazardous Substances Data)

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 5888-29-9 diethyl(methoxymethyl)amine 
• 109-89-7 diethylamine 
• 98-86-2 acetophenone 
• 74-95-3 1,1-dibromomethane 
• 50-00-0 formaldehyd 

Relevant articles and documents

A NOVEL AMINOMETHYLATION OF SILYL ENOL ETHERS WITH AMINOMETHYL ETHERS CATALYZED BY IODOTRIMETHYLSILANE OR TRIMETHYLSILYL TRIFLUOROMETHANESULFONATE

The iodotrimethylsilane-catalyzed reaction of silyl enol ethers with aminomethyl ethers in acetonitrile gives aminomethylation products of the corresponding ketones readily.The reaction can also be catalyzed by trimethylsilyl trifluoromethanesulfonate in dichloromethane.

Dibromomethane as one-carbon source in organic synthesis: Microwave-accelerated α-methylenation of ketones with dibromomethane and diethylamine

The reactivity of aryl alkyl ketone with a preheated mixture of dibromomethane and diethylamine is poor and gives an α-methylenation product in very low yield even under refluxing condition. It can be accelerated dramatically by microwave irradiation. Under microwave condition, the cyclic 1,3-dicarbonyls, aryl alkyl ketones, heteroaryl alkyl ketones and acyclic benzyl ketone give α-methylenation products in modest to good yields.