28458-68-6

Basic information

• Product Name: 1-N-tert-Butylbenzene-1,2-diaMine
• Synonyms: 1-N-tert-Butylbenzene-1,2-diaMine;2-N-tert-butylbenzene-1,2-diamine;N1-(tert-Butyl)benzene-1,2-diamine
• CAS NO: 28458-68-6
• Molecular Formula: C₁₀H₁₆N₂
• Molecular Weight: 164.24744
• Mol File: 28458-68-6.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-N-tert-Butylbenzene-1,2-diaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-tert-Butylbenzene-1,2-diaMine(28458-68-6)
• EPA Substance Registry System: 1-N-tert-Butylbenzene-1,2-diaMine(28458-68-6)

Safety Data

• Hazardous Substances Data: 28458-68-6(Hazardous Substances Data)

Usage

General Description

1-N-tert-Butylbenzene-1,2-diamine is a chemical compound with the molecular formula C14H24N2. It is a type of diamine, which means it contains two amino groups. The compound has a tert-butyl group attached to the nitrogen atoms, providing steric hindrance and increasing its stability. 1-N-tert-Butylbenzene-1,2-diamine is used as a building block in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also employed as a curing agent for epoxy resins and as a catalyst in organic reactions. The chemical's structure and properties make it valuable in the production of a wide range of industrial and research applications.

Upstream product

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Downstream Products

• 76060-04-3 2-(2-nitrophenyl)-1-(t-butyl)-2,3-dihydrobenzimidazole 
• 17582-96-6 1-(tert-butyl)-1H-benzimidazole 
• 1189055-89-7 1-tert-butyl-2-(N-phenylamino)benzimidazole 
• 76060-07-6 2-(2-nitrophenyl)-1-(t-butyl)benzimidazole 
• 76060-11-2 2-(2-azidophenyl)-1-(t-butyl)benzimidazole 
• 76060-10-1 2-(2-aminophenyl)-1-(t-butyl)benzimidazole 
• 180207-78-7 (3,5-Dimethyl-piperazin-1-yl)-[3-(4-methoxy-phenyl)-4H-imidazo[1,5-a]quinoxalin-5-yl]-methanone 

Relevant articles and documents

Molecular Scissors for Tailor-Made Modification of Siloxane Scaffolds

The controlled design of functional oligosiloxanes is an important topic in current research. A consecutive Si?O?Si bond cleavage/formation using siloxanes that are substituted with 1,2-diaminobenzene derivatives acting as molecular scissors is presented.

TREX1 INHIBITORS AND USES THEREOF

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds for inhibiting three prime repair exonuclease 1 ("TREX1").

Synthetic, structural, and computational investigations of N-alkyl benzo-2,1,3-selenadiazolium iodides and their supramolecular aggregates

Despite their versatility, the application of telluradiazoles as supramolecular building blocks is considerably constrained by their sensitivity to moisture. Albeit more robust, their selenium analogues form weaker supramolecular interactions. These, however, are enhanced when one nitrogen atom is bonded to an alkyl group. Here we investigate general methods for the synthesis of such derivatives. Methyl, iso-propyl and tert-butyl benzo-2,1,3-selenadiazolium cations were prepared by direct alkylation or cyclo-condensation of the alkyl-phenylenediamine with selenous acid. While the former reaction only proceeds with the primary and tertiary alkyl iodides, the latter is very efficient. Difficulties reported in earlier literature are attributable to the formation of adducts of benzoselenadiazole with its alkylated cations and side reactions initiated by aerobic oxidation of iodide. However, the cations themselves are resilient to oxidation and stable in acidic to neutral aqueous medium. X-ray crystallography was used in the identification and characterization of the following compounds: [C6H4N2(R)Se]+X-, (R = CH(CH3)2, C(CH3)3; X = I-, I3-], [C6H4N2(CH3)Se]+I-, and [C6H4N2Se][C6H4N2(CH3)Se]2I2. Formation of Se?N secondary bonding interactions (chalcogen bonds) was only observed in the last structure as anion binding to selenium is a strong competitor. The relative strengths of those forces and the structural preferences they enforce were assessed with DFT-D3 calculations supplemented by AIM analysis of the electron density.