28459-83-8

Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 9071824 is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, featuring a fluorine atom and a methyl group, allows for the development of new drugs with improved properties, such as enhanced solubility, stability, and bioavailability.
Used in Agrochemical Industry:
In the agrochemical industry, CHEMBRDG-BB 9071824 serves as a key building block for the creation of novel agrochemicals, such as pesticides and herbicides. Its aromatic structure and functional groups can be utilized to design molecules with increased efficacy and selectivity, leading to more effective and environmentally friendly agricultural products.
Used in Organic Synthesis:
CHEMBRDG-BB 9071824 is used as a versatile starting material in organic synthesis for the preparation of a wide range of organic compounds. Its aromatic core and functional groups can be further modified through various chemical reactions, enabling the synthesis of complex molecules with diverse applications in fields such as materials science, fragrances, and dyes.

InChI:InChI=1/C11H15N/c1-11(2)7-9-5-3-4-6-10(9)8-12-11/h3-6,12H,7-8H2,1-2H3

Upstream product

• 28460-55-1 3,3-dimethyl-3,4-dihydroisoquinoline 
• 5669-14-7 2,2-dimethyl-3-phenylpropanoic acid 
• 14248-22-7 methyl 2,2-dimethyl-3-phenylpropionate 
• 100-39-0 benzyl bromide 
• 122-09-8 Phentermin 
• 91-20-3 naphthalene 
• 200631-40-9 3,3-dimethyl-2-tosyl-1,2,3,4-tetrahydroisoquinoline 
• 110871-36-8 4-methyl-N-(2-methyl-1-phenylpropan-2-yl)benzenesulfonamide 
• 1197-21-3 phentermine hydrochloride 

Downstream Products

• 148671-62-9 3,3-dimethyl-3,4-dihydroisoquinoline N-oxide 
• 1400303-72-1 3,3-dimethyl-1-(p-tolyl)-3,4-dihydroisoquinoline 2-oxide 
• 1400303-73-2 3,3-dimethyl-1-(3,4,5-trimethoxyphenyl)-3,4-dihydroisoquinoline 2-oxide 
• 1400303-74-3 1-(4-(methoxycarbonyl)phenyl)-3,3-dimethyl-3,4-dihydroisoquinoline 2-oxide 
• 1265633-66-6 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)(3,3-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone 

Relevant academic research and scientific papers

SYNTHESIS AND ACYLATION OF 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES

1,2,3,4-Tetrahydroisoquinolines were synthesized, and their acylation was studied.

SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted, saturated and unsaturated N-heterocyclic carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

Fast Pd- and Pd/Cu-catalyzed direct C - H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters

Cocatalysis by pivalic acid or copper bromide allows a very fast, clean, and high-yielding palladium-catalyzed coupling of a large array of aryl, thienyl, and pyridyl halides with cyclic nitrones, including DMPO. The study of the reaction conditions, scope, and mechanism is presented. Applied to the chiral nitrone MiPNO, this transformation provides a straightforward access to enantiopure a-methyl α-arylglycine esters.

PICTET-SPENGLER REACTION FOR THE SYNTHESIS OF TETRAHYDROISOQUINOLINES AND RELATED HETEROCYCLIC COMPOUNDS

A commercial scale process for the production of tetrahydroisoquinolines and related heterocyclics by reaction, in mildly acidic conditions, of aryl N-sulfonylethylamines in the presence of suitable Lewis acid, and a compound capable of in situ generation

Pictet-Spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds

A commercial scale process for the production of tetrahydroisoquinolines and related heterocyclics by reaction, in mildly acidic conditions, of aryl N-sulfonylethylamines in the presence of a suitable Lewis acid, and a compound capable of in situ generati