284686-19-7 Usage
Description
2-Chloro-N-[2-(cyclopropylamino)-4-methyl-3-pyridinyl]-3-pyridinecarboxamide is a chemical compound with a complex structure, characterized by its dark brown solid appearance. It is an intermediate in the preparation of Nevirapine metabolites, which are relevant in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
2-Chloro-N-[2-(cyclopropylamino)-4-methyl-3-pyridinyl]-3-pyridinecarboxamide is used as an intermediate in the synthesis of Nevirapine metabolites for the development of antiretroviral drugs. Its role in the production process is crucial for creating medications that help combat retroviral infections, such as HIV.
Chemical Properties:
2-Chloro-N-[2-(cyclopropylaMino)-4-Methyl-3-pyridinyl]-3-pyridinecarboxaMide is described as a dark brown solid, which is an important characteristic for its identification and handling in various chemical processes and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 284686-19-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,6,8 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 284686-19:
(8*2)+(7*8)+(6*4)+(5*6)+(4*8)+(3*6)+(2*1)+(1*9)=187
187 % 10 = 7
So 284686-19-7 is a valid CAS Registry Number.
284686-19-7Relevant articles and documents
Synthesis of five nevirapine metabolites
Grozinger, Karl G.,Byrne, Denis P.,Nummy, Laurence J.,Ridges, Michael D.,Salvagno, Annette
, p. 229 - 239 (2007/10/03)
Nevirapine (1) is a non-nucleoside reverse transcriptase inhibitor marketed for HIV treatment by Boehringer Ingelheim as Viramune since 1996. In vitro studies of nevirapine biotransformation using human liver microsomes demonstrated the formation of five major metabolites. This paper describes the syntheses of these metabolites.
