284686-21-1 Usage
Chemical Properties
Light Brown Solid
Uses
Intermediate in the preparation of Nevirapine metabolites.
Check Digit Verification of cas no
The CAS Registry Mumber 284686-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,6,8 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 284686-21:
(8*2)+(7*8)+(6*4)+(5*6)+(4*8)+(3*6)+(2*2)+(1*1)=181
181 % 10 = 1
So 284686-21-1 is a valid CAS Registry Number.
284686-21-1Relevant articles and documents
Synthesis of five nevirapine metabolites
Grozinger, Karl G.,Byrne, Denis P.,Nummy, Laurence J.,Ridges, Michael D.,Salvagno, Annette
, p. 229 - 239 (2007/10/03)
Nevirapine (1) is a non-nucleoside reverse transcriptase inhibitor marketed for HIV treatment by Boehringer Ingelheim as Viramune since 1996. In vitro studies of nevirapine biotransformation using human liver microsomes demonstrated the formation of five major metabolites. This paper describes the syntheses of these metabolites.
