284686-21-1 Usage
Uses
Used in Pharmaceutical Industry:
3-BroMo Nevirapine is used as an intermediate in the synthesis of Nevirapine metabolites for the development of antiretroviral drugs. Its role in the production process is crucial, as it contributes to the effectiveness of the final drug product in treating HIV and AIDS.
As an intermediate, 3-BroMo Nevirapine plays a significant role in the chemical reactions that lead to the formation of the desired Nevirapine metabolites. These metabolites are essential for the drug's therapeutic effects, making 3-BroMo Nevirapine a vital component in the pharmaceutical industry's fight against HIV and AIDS.
Check Digit Verification of cas no
The CAS Registry Mumber 284686-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,6,8 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 284686-21:
(8*2)+(7*8)+(6*4)+(5*6)+(4*8)+(3*6)+(2*2)+(1*1)=181
181 % 10 = 1
So 284686-21-1 is a valid CAS Registry Number.
284686-21-1Relevant articles and documents
Synthesis of five nevirapine metabolites
Grozinger, Karl G.,Byrne, Denis P.,Nummy, Laurence J.,Ridges, Michael D.,Salvagno, Annette
, p. 229 - 239 (2007/10/03)
Nevirapine (1) is a non-nucleoside reverse transcriptase inhibitor marketed for HIV treatment by Boehringer Ingelheim as Viramune since 1996. In vitro studies of nevirapine biotransformation using human liver microsomes demonstrated the formation of five major metabolites. This paper describes the syntheses of these metabolites.
