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Usage

Uses

Used in Pharmaceutical Industry:
1-Fluoro-3-(methoxymethyl)benzene is used as an intermediate for the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and medications. Its unique chemical properties allow for the creation of molecules with specific therapeutic effects, enhancing the range of available treatments for various medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Fluoro-3-(methoxymethyl)benzene is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these products helps improve their effectiveness in controlling pests and weeds, thereby increasing crop yields and ensuring food security.
Used in Organic Compounds Synthesis:
1-Fluoro-3-(methoxymethyl)benzene is used as a building block in the synthesis of various organic compounds, including specialty chemicals and advanced materials. Its versatility in organic chemical reactions enables the creation of a wide range of products with diverse applications, from industrial processes to consumer goods.
Used in Research and Development:
As an important reagent in organic chemical reactions, 1-Fluoro-3-(methoxymethyl)benzene is employed in research and development laboratories. Scientists and researchers use 1-FLUORO-3-(METHOXYMETHYL)BENZENE to explore new chemical reactions, develop innovative materials, and advance the understanding of organic chemistry.

InChI:InChI=1S/C8H9FO/c1-10-6-7-3-2-4-8(9)5-7/h2-5H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 456-47-3 3-fluoro-benzenemethanol 
• 124-41-4 sodium methylate 
• 456-42-8 m-fluorobenzyl chloride 
• 74-88-4 methyl iodide 
• 352-70-5 m-Fluorotoluene 
• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 

Relevant academic research and scientific papers

SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING

A compound of formula (I), wherein: R1 is selected from (i) H, (ii) C3-6cycloalkyl, (iii) C3-7heterocyclyl optionally substituted with a group selected from: methyl and ester, and (iv) linear or branched C1-4alkyl optionally substituted with a group selected from: alkoxy, amino, amido, acylamido, acyloxy, alkyl carboxyl ester, alkyl carbamoyl, alkyl carbamoyl ester, phenyl, phosphonate ester, C3-7heterocyclyl optionally substituted with a group selected from methyl and oxo, and a naturally occurring amino acid, optionally N-substituted with a group selected from methyl, acetyl and boc; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC, and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and CH2NMe2; the remainder of RA, RB, RC, and RD, (if present) are H; Y is O, NH or CH2; RY is selected from: (RYA) and (RYB).

Physical organic chemistry of transition metal carbene complexes. 24. Thermodynamic and kinetic acidities of phenyl-substituted (benzylmethoxycarbene)pentacarbonylchromium(0) complexes. Is there a transition-state imbalance?

A kinetic study of the reversible deprotonation of phenyl-substituted (benzylmethoxycarbene)pentacarbonylchromium(0) complexes by OH- and by a series of primary aliphatic and a series of secondary alicyclic amines in 50% MeCN-50% water (v/v) at 25°C is reported. Bronsted αCH values (dependence on carbene complex acidity) and βB values (dependence on amine basicity) were determined. According to current notions about proton transfers involving carbon acids activated by φ-acceptors, αCH was expected to substantially exceed βB, the result of transition-state imbalances that are characteristic of such reactions. However we find that αCH and βB have essentially the same values, which are close to0.5. It is shown that these findings do not indicate the absence of an imbalance but rather suggest that the manifestation of the imbalance is masked by the φ-donor effect (3H-Z ? 3H-Z±) of the methoxy group.

Correlation of the rates of solvolysis of (arylmethyl)methylphenyl-sulfonium ions

The specific rates of solvolysis of the benzylmethylphenylsulfonium ion (prepared as the trifluoromethanesulfonate salt) and five benzylic ring-substituted derivatives can be satisfactorily correlated using NT solvent nucleophilicity values. Addition of a secondary term, governed by the aromatic ring parameter (I), shows the sensitivities towards changes in this parameter to fall and those towards changes in NT to rise with increasing electron-withdrawing ability of the substituent. The Hammett ρ values with electron-withdrawing substituents (based on ρ+ values) vary from -0.9 in 95% acetone to -1.8 in 97% 2,2,2-trifluoroethanol. These Grunwald-Winstein and Hammett analyses are compared to those previously reported, with essentially the same solvents and substituents, for solvolyses of arylmethyl p-toluenesulfonates.