2850-21-7Relevant articles and documents
3-PHENYLSULPHONYL-QUINOLINE DERIVATIVES AS AGENTS FOR TREATING PATHOGENIC BLOOD VESSELS DISORDERS
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Paragraph 0351, (2021/04/23)
The disclosure provides compounds, and compositions, including pharmaceutical compositions, kits that include the compounds, and methods of using (or administering) and making the compounds. The disclosure further provides compounds or compositions thereof for use in a method of modulating PLXDC1 (TEM7) and/or PLXDC2 or killing pathogenic blood vessles. The disclosure further provides compounds or compositions thereof for use in a method of treating a disease, disorder, or condition that is mediated, at least in part, by PEDF receptors or by angiogenesis.
Novel sulphone acid derivative, preparation method thereof and application of novel sulphone acid derivative as medicine
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Paragraph 0128; 0130, (2017/07/20)
The invention relates to a novel sulphone acid derivative show in a formula (I), a preparation method thereof and application of a medicine composition containing the derivative in preparing medicines for treating diabetes and metabolic syndrome. The sulphone acid derivative has excellent in-vivo blood glucose decreasing activity, and can be used for preventing or treating diabetes. (The formula is shown in the description).
Bu4NI-Catalyzed Cross-Coupling between Sulfonyl Hydrazides and Diazo Compounds to Construct β-Carbonyl Sulfones Using Molecular Oxygen
Wang, Yaxiong,Ma, Liang,Ma, Meihua,Zheng, Hao,Shao, Ying,Wan, Xiaobing
supporting information, p. 5082 - 5085 (2016/10/14)
A new cross-coupling reaction between sulfonyl hydrazides and diazo compounds has been established, leading to a variety of β-carbonyl sulfones in good yields. This methodology was distinguished by simple manipulation, easily available starting materials, and wide substrate scope. A plausible mechanism involving a radical process was proposed based upon the experimental observations and literature.
