28519-31-5

Usage

InChI:InChI=1/C11H16O2S2/c1-4-10(3)13-15(12,14)11-7-5-9(2)6-8-11/h5-8,10H,4H2,1-3H3

Upstream product

• 109-65-9 1-bromo-butane 
• 28519-50-8 potassium thiotosylate 
• 150-50-5 merphos 
• 104-15-4 toluene-4-sulfonic acid 
• 629-45-8 dibutyl disulfide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 109-79-5 n-butanethiol 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 542-69-8 1-iodo-butane 
• 3753-27-3 sodium 4-methylbenzenesulfonothioate 
• 78-48-8 S,S,S-tributylphosphorotrithioate 
• 536-57-2 p-toluene sulfinic acid 

Downstream Products

• 37456-99-8 2-(Butylthio)cyclohexanon 
• 69187-12-8 4-methylphenyl n-butyl disulfide 

Relevant academic research and scientific papers

Ammonium iodide-mediated electrosynthesis of unsymmetrical thiosulfonates from arenesulfonohydrazides and thiols

Unsymmetrical thiosulfonates were synthesized from thiols and arenesulfonohydrazides by their electrolysis in undivided cell equipped with graphite anode and stainless steel cathode under high current density applying NH4I both as a redox catal

Copper-Catalyzed Oxidative Trifunctionalization of Olefins: An Access to Functionalized β-Keto Thiosulfones

Aerobic oxidative trifunctionalization of olefins for the synthesis of functionalized β-keto thiosulfones has been described. The transformation proceeds through molecular oxygen activation under copper catalysis and forms the two new C-S bonds in a single operation using mild conditions. A novel Cu-catalyzed sulfonyl radical addition/oxidation/funtionalization relay mechanism was proposed for the discovered reaction.

Oxidative coupling of dichalcogenides with sodium sulfinates via copper-catalyzed cleavage of s-s and se-se bonds

A copper-catalyzed sulfonylation of disulfides was achieved using sodium sulfinates in air. The reaction formed various sulfur-sulfone bonds efficiently and afforded thiosulfonates in good yields. Selenosulfonates could also be prepared with this procedure. Furthermore, both chalcogenide groups on the dichalcogenides were available in these reactions.

Copper-catalyzed synthesis of thiosulfonates by oxidative coupling of thiols with sodium sulfinates

The copper-catalyzed sulfonylation of thiols was performed by using sodium sulfinates under an oxygen atmosphere. The procedure afforded thiosulfonates in good yields by using a CuI-Phen?H2O (Phen = 1,10-phenanthroline) catalyst and tolerated numerous combinations of arene- and alkanethiols with sodium sulfinates. Furthermore, it was found that the coupling of diaryl disulfides with sodium arylsulfinates proceeded in air and both sulfide groups on the disulfide were available.

MUTILIN DERIVATIVE HAVING HETEROCYCLIC AROMATIC RING CARBOXYLIC ACID STRUCTURE IN SUBSTITUENT AT 14-POSITION

To provide a novel mutilin derivative having a substitution at the 14-position, which is a novel mutilin analogue exhibiting a potent and broad antimicrobial action against Gram-positive bacteria and Gram-negative bacteria including various drug-resistant bacteria, and which is expected to be useful as an agent for treating infectious diseases. A mutilin derivative represented by the following general formula (1): or a pharmaceutically acceptable addition salt thereof.

Reaction of Thio Acid S-Esters with p-Toluenesulfonic Acid: A Facile Synthesis of p-Toluenethiosulfonic S-Esters

Treatment of dehydrated p-toluenesulfonic acid (TsOH) with thio acid S-esters such as carbothioic acid and phosphorus thio acid S-esters in refluxing solvent resulted in the formation of p-toluenethiosulfonic S-esters (TsSR).The reaction of trialkyl phosphorotrithioites with TsOH provided the corresponding TsSR in relatively good yields.This constitutes a new and facile method for the preparation of unsymmetrical thiosulfonic S-esters.Keywords-p-toluenesulfonic acid; trialkyl phosphorotrithioite; trialkyl phosphorotrithiolate; carbothioic acid S-ester; p-toluenethiosulfonic S-ester; dialkyl disulfide.

A Kinetic Study of the Silver(I) Ion-assisted Synthesis of Thiosulphonate Esters from Aliphatic Disulphides

Kinetic studies confirm that the silver(I) ion-promoted reaction of disulphides with sulphinate ions proceeds via formation of a disulphide-Ag+ complex.Nucleophilic attack by sulphinate sulphur at the sulphenyl centre of the complex leads to sylver alkyl sulphide and thiosulphonate.Under favoruable conditions the 1:1 disulphide-silver complex can be isolated.

New Synthetic Methods, 9. - S-Alkyl 4-Methylbenzenethiosulfonates, Excellent Reagents for α-Thiolation of Cyclic Ketones

S-Alkyl 4-methylbenzenethiosulfonates, easily prepared by alkylation of commercially available potassium 4-methylbenzenethiosulfonate in dry dimethylformamide, thiolate enolates of cyclic ketones in α position in high yield.