28534-06-7

Basic information

• Product Name: 2-(1-phenylethyl)aniline
• CAS NO: 28534-06-7
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.2756
• Mol File: 28534-06-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 327.9°C at 760 mmHg
• Flash Point: 159.8°C
• Density: 1.047g/cm³
• Vapor Pressure: 0.000196mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 2-(1-phenylethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-phenylethyl)aniline(28534-06-7)
• EPA Substance Registry System: 2-(1-phenylethyl)aniline(28534-06-7)

Safety Data

• Hazardous Substances Data: 28534-06-7(Hazardous Substances Data)

Usage

Physical appearance

White to pale yellow solid.

Molecular weight

197.28 g/mol.

Usage

Precursor in the synthesis of various organic compounds.

Applications

Production of pharmaceuticals, dyes, and other fine chemicals.

Safety precautions

Potentially harmful if in contact with skin or ingested.

Upstream product

• 98-85-1 1-Phenylethanol 
• 62-53-3 aniline 
• 779-54-4 phenyl(1-phenylethyl)amine 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 52744-71-5 1-(2-aminophenyl)-1-phenylethan-1-ol 
• 551-93-9 2-aminoacetophenone 
• 100-58-3 phenylmagnesium bromide 
• 100-42-5 styrene 
• 64097-92-3 2-(1-phenylvinyl)aniline 
• 142-04-1 aniline hydrochloride 
• 103-84-4 Acetanilid 

Downstream Products

• 101174-82-7 N,N'-diphenyl-N-(1-phenyl-ethyl)-urea 

Relevant articles and documents

Zeolite catalyzed hydroarylation of alkenes with aromatic amines under organic ligand-free conditions

The hydroarylation of alkenes with aromatic amines is recognized as the most atom-economical and straightforward approach to obtain functional aromatic amines, which are versatile building blocks in organic synthesis and material chemistry. However, controllable synthesis of single hydroarylation product is still a significant challenge because hydroarylation reaction often delivers four hydroarylation products and hydroamination products are also produced during the reaction. Herein, we report the first example of heterogeneous zeolite catalyzed hydroarylation of styrene and norbornene with aniline derivatives under organic ligand-free conditions. With the USY zeolite as catalyst, a wide scope of alkenes and aromatic amines with various functional groups are smoothly converted into the corresponding products in 48–95% yields with high regioselectivity. Detailed characterizations revealed that Lewis acid can promote Hofmann-Martius rearrangement of hydroamination products toward hydroarylation products, resulting in high selectivity for hydroarylation products. In addition, it could be found that the weak acid sites of zeolite play a key role in forming hydroarylation products. Furthermore, the catalyst can be reused at least 10 times without obvious deactivation. This work may promote the development of heterogeneous catalyst system for alkene hydroarylation.

Cobalt-Catalyzed Hydroarylations and Hydroaminations of Alkenes in Tunable Aryl Alkyl Ionic Liquids

Tunable aryl alkyl ionic liquids (TAAILs) are a promising class of imidazolium- or triazolium-based ionic liquids. Contrary to "standard" all-alkyl ionic liquids, these carry an aryl ring together with a linear or branched alkyl chain. Their application i

Intramolecular addition of triarylmethanes to alkynes promoted by KOtBu/DMF: A synthetic approach to indene derivatives

A method for the intramolecular addition of triarylmethanes to alkynes has been developed. The reaction was efficiently promoted by KOtBu/DMF without any transition-metal catalyst. A variety of indene derivatives were prepared in moderate to good yields. A cascade cyclization of 2-alkyl-substituted substrates at elevated reaction temperature gave bicyclic indene derivatives. The reaction is proposed to proceed through the generation of a triphenylmethyl radical. Indene derivatives were prepared by the intramolecular addition of triarylmethanes to alkynes promoted by KOtBu/DMF. A cascade cyclization of 2-alkyl-substituted substrates at elevated reaction temperature gave bicyclic indene derivatives. A free-radical reaction mechanism is proposed.