28546-59-0

Upstream product

• 74-87-3 methylene chloride 
• 2894-71-5 7-chloro-1,3-dihydro-5-(o-chlorophenyl)-2H-1,4-benzodiazepine-2-thione 
• 2894-67-9 delorazepam 
• 74-88-4 methyl iodide 
• 2958-36-3 (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone 
• 5504-92-7 2-(2-bromo-acetylamino)-5,2'-dichloro-benzophenone 
• 106-47-8 4-chloro-aniline 
• 609-65-4 o-chlorobenzoyl chloride 

Downstream Products

• 39256-20-7 8-chloro-6-(2-chloro-phenyl)-1-diethoxymethyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine 
• 2894-67-9 delorazepam 
• 82874-38-2 7-chloro-5-(2-chlorophenyl)-4,5-dihydro-2-(2-dimethylaminoethylthio)-4-methyl-3H-1,4-benzodiazepine 
• 80590-06-3 {[1-(2-Amino-5-chloro-phenyl)-1-(2-chloro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid isopropyl ester 
• 80590-09-6 {[1-(2-Amino-5-chloro-phenyl)-1-(2-chloro-phenyl)-meth-(E)-ylidene]-amino}-acetic acid isopropyl ester 
• 80590-05-2 {[1-(2-Amino-5-chloro-phenyl)-1-(2-chloro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid ethyl ester 
• 80590-08-5 {[1-(2-Amino-5-chloro-phenyl)-1-(2-chloro-phenyl)-meth-(E)-ylidene]-amino}-acetic acid ethyl ester 
• 80590-04-1 {[1-(2-Amino-5-chloro-phenyl)-1-(2-chloro-phenyl)-meth-(Z)-ylidene]-amino}-acetic acid methyl ester 
• 80590-07-4 methyl (E)-<2-amino-5-chloro-α-(2-chlorophenyl)benzylidene>-aminoacetate 
• 82874-36-0 7-chloro-5-(2-chlorophenyl)-2,3-dihydro-4-methyl-2-oxo-1H-1,4-benzodiazepinium iodide 
• 82874-37-1 7-chloro-5-(2-chlorophenyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-thione 
• 82881-11-6 7-chloro-5-(2-chlorophenyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one 
• 67373-10-8 7-chloro-5-(2-chloro-phenyl)-2-methoxy-3H-benzo[e][1,4]diazepine 

Relevant academic research and scientific papers

Synthesis and spectral determination of new derivatives of 1-[(p-substituted)phenyl]-3a-[(o- and p-substituted)phenyl]-5-chloro-9- methylthio-10,3a-dihydro-[1,2,4]-oxadiazolo[2,3-b][1,4]benzodiazepines

(Chemical Equation Presented) A new synthesis to obtain eight novel derivatives of 1-[(p-substituted)phenyl]-3a-[(o- and p-substituted)-phenyl]-5- chloro-9-methylthio-10,3a-dihydro-[1,2,4]-oxadiazolo[2,3-b][1,4]benzodiazepines with possible biological and

Synthesis and spectral properties of 2-[(o- and p-substituted)aminophenyl]-3H-5-[(o- and p-substituted)phenyl]-7-chloro-1,4-benzodiazepines

A series of twelve new 2-[(o- and p-substituted)aminophenyl]-3H-5-[(o- and p-substituted)phenyl]-7-chloro-1,4-benzodiazepines, which have possible pharmacological properties has been obtained. The synthesis was carried out following six steps. The structure of all products was corroborated by ir, 1H nmr, 13C nmr and ms. In addition for the compound 2-(o-chloroaminophenyl)-3H-5-(o-fluorophenyl)-7-chloro-1,4-benzodiazepine 7, its structure was confirmed by X-ray diffraction.

Benzodiazepines. 4, 2 Oxyamino 5 phenyl 3H 1,4 benzodiazepines

A series of 2 oxyamino 5 phenyl 3H 1,4 benzodiazepines has been prepared by the reaction of oxyamine derivatives with 1,3 dihydro 5 phenyl 2H 1,4 benzodiazepine 2 thiones. Pharmacologic testing in animals has shown that some of these compounds have interesting CNS depressant activity and suggests that they will have useful anxiolytic activity in man.