28586-52-9Relevant academic research and scientific papers
Bioactive 3,4,5-substituted benzodiazepine 2-one drug molecules and preparation method thereof
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Paragraph 0025; 0026, (2018/04/26)
The invention discloses bioactive 3,4,5-substituted benzodiazepine 2-one drug molecules and a preparation method thereof and belongs to the technical field of drug synthesis. The technical scheme is characterized in that the structure of the compounds is shown in the description, wherein R1 is methyl, pyridyl, phenyl or isopropyl; R1 and R2 are selected from methyl, ethyl or phenyl independently respectively. Compared with the prior art, the compounds and the preparation method have the following beneficial effects: the synthesis method is simple, the molecular structure is novel, and the compounds have an inhibition effect on the leukemia cell line K562 and the breast cancer cell MCF-7 and are expected to be further popularized and applied.
