286371-53-7

Upstream product

• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 100-39-0 benzyl bromide 
• 205448-31-3 4-chloro-6-methoxy-7-hydroxyquinoline 
• 205448-29-9 7-benzyloxy-4-hydroxy-6-methoxyquinoline 
• 75665-73-5 1-(2-amino-4-(benzyloxy)-5-methoxyphenyl)ethanone 
• 75665-88-2 1-(4-(benzyloxy)-5-methoxy-2-nitrophenyl)ethanone 
• 1835-11-6 4-benzyloxy-3-methoxyacetophenone 
• 286371-49-1 7-(benzyloxy)-4-chloro-6-methoxyquinoline 
• 52671-64-4 4-Amino-3-chlorophenol hydrochloride 

Downstream Products

• 286371-54-8 N-(4-{[7-(Benzyloxy)-6-methoxy-4-quinolyl]oxy}-2-chlorophenyl)-N'-(2,4-difluorophenyl)-urea 
• 1622396-74-0 C₂₄H₂₀FN₃O₄ 
• 1622396-75-1 C₃₀H₂₉ClFN₃O₆ 
• 1622396-76-2 C₃₀H₃₀FN₃O₆ 
• 1622396-77-3 C₂₈H₂₅ClFN₃O₆ 
• 1622396-78-4 C₂₈H₂₆FN₃O₆ 
• 1622343-43-4 C₃₅H₃₆ClFN₄O₆ 
• 1622385-35-6 C₃₅H₃₇FN₄O₆ 
• 1622343-31-0 C₃₀H₂₉ClFN₃O₆ 
• 1622342-97-5 C₂₄H₁₉ClFN₃O₄ 
• 1622343-07-0 C₃₄H₃₆ClFN₄O₅ 
• 1622342-89-5 C₃₁H₂₅ClFN₃O₄ 

Relevant academic research and scientific papers

THERAPEUTIC COMPOUNDS AND USES THEREOF

Described herein are compounds of Formula (I) or Formula (VI), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I) or Formula (VI) and pharmaceutical compositions thereof that are mucus penetrating. Methods of using the compounds or pharmaceutical compositions thereof for treating diseases are also provided.

QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES

An object of the present invention is to provide compounds which have antitumor activity and do not change cytomorphosis. Disclosed are compounds represented by formula (I) and a pharmaceutically acceptable salts and solvates thereof and pharmaceutical compositions comprising said compounds: wherein X and Z each independently represent CH or N; R1 to R3 represent H, substituted alkoxy, unsubstituted alkoxy or the like; R4 represents H; R5 to R8 represent H, halogen, alkyl, alkoxy, alkylthio, nitro, or amino, provided that R5 to R8 do not simultaneously represent H; R9 and R10 represent H, alkyl, or alkylcarbonyl; and R11 represents alkyl, alkenyl, alkynyl, or aralkyl.