28719-00-8 Usage
Uses
Used in Organic Synthesis:
6-Cyano-2-(4-cyanophenyl)indole is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. The presence of cyano groups in its structure enables it to participate in a wide range of chemical reactions, such as nucleophilic addition, electrophilic substitution, and reductive amination, making it a valuable component in the development of new molecules with desired properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-Cyano-2-(4-cyanophenyl)indole is used as a key intermediate in the synthesis of drug candidates with potential therapeutic applications. Its structural features can be exploited to design and develop novel compounds with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability. The cyano groups in its structure can also be used to introduce functional groups that can modulate the pharmacokinetic and pharmacodynamic properties of the resulting drug molecules.
Used in Agrochemical Industry:
6-Cyano-2-(4-cyanophenyl)indole is also utilized in the agrochemical industry as a starting material for the synthesis of new pesticides and other crop protection agents. Its unique structural features can be employed to create molecules with improved biological activity, selectivity, and environmental compatibility. The cyano groups present in its structure can be used to introduce functional groups that can enhance the pesticidal properties of the resulting compounds, such as increased stability, reduced toxicity, and improved target specificity.
Check Digit Verification of cas no
The CAS Registry Mumber 28719-00-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,7,1 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 28719-00:
(7*2)+(6*8)+(5*7)+(4*1)+(3*9)+(2*0)+(1*0)=128
128 % 10 = 8
So 28719-00-8 is a valid CAS Registry Number.
28719-00-8Relevant academic research and scientific papers
Preparation method of 4', 6-diamidinyl-2-phenylindole dihydrochloride
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, (2021/06/26)
The invention discloses a preparation method of 4', 6-diamidinyl-2-phenylindole dihydrochloride, which comprises the following steps: firstly, taking 6-substituted indole as a raw material, and reacting with formamide under the action of a reaction solvent and a first catalyst to prepare 6-cyano indole; then performing a reactionthe 6-cyanoindole and the 4-substituted cyanobenzene under the action of a second catalyst, and obtaining 6-cyano-2-(4 '-cyanophenyl) indole; using 6-cyano-2-(4'-cyanophenyl) indole as a raw material and reacting with alcohol containing a substituent group under the action of a third catalyst, and obtaining 4', 6-bis (substituent group-containing methyleneimic acid ester)-2-phenylindole dihydrochloride; finally, continuously reacting with ammonium chloride, and obtaining the 4', 6-diamidinyl-2-phenylindole dihydrochloride. The design route is reasonable in design, the process safety is high, the method is friendly to operators, the cost is low, and the requirement for industrial production of products can be fully met.
Antiprotozoal diamidines
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, (2008/06/13)
Diamidines of the formula STR1 wherein X is a propylene, isobutylene, guanidine, pyrrole, tetrazole, imidazole or substituted imidazole group; and 2-[4-(2-imidazolinyl)phenyl]-6-(2-imidazolinyl)indole, are useful in the treatment of certain protozoal infections in mammals, particularly in cattle.
