287952-21-0

Basic information

• Product Name: 4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester
• Synonyms: 4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester
• CAS NO: 287952-21-0
• Molecular Weight: 375.388
• Mol File: 287952-21-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester(287952-21-0)
• EPA Substance Registry System: 4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester(287952-21-0)

Safety Data

• Hazardous Substances Data: 287952-21-0(Hazardous Substances Data)

Upstream product

• 50824-05-0 4-trifluoromethoxybenzyl bromide 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 681482-45-1 4-((4-(trifluoromethoxy)benzyl)oxy)piperidine 
• 287952-22-1 4-((4-(trifluoromethoxy)benzyl)oxy)piperidine hydrochloride 
• 1332302-38-1 N,2-dimethyl-3-((4-(4-((4-(trifluoromethoxy)benzyl)oxy)piperidin-1-yl)-1,3,5-triazin-2-yl)amino)benzamide 
• 1332302-39-2 2-chloro-4-(4-((4-(trifluoromethoxy)benzyl)oxy)piperidin-1-yl)-1,3,5-triazine 
• 1211875-20-5 4-(4-(trifluoromethoxy)benzyloxy)piperidine trifluoroacetate salt 
• 1211866-85-1 N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide 
• 287952-67-4 4-(4-(trifluoromethoxy)phenoxy)piperidine 
• 1346017-61-5 (S)-N-(6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-3-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl) propanamide 
• 1346017-36-4 (S)-N-(6,7-dihydro-2-nitro-5H-imidazo [2,1-b][1,3]oxazin-6-yl)-2-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)acetamide 
• 1346017-95-5 3-(2-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)ethoxy)propionic acid 
• 1346017-94-4 ethyl 3-(2-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)ethoxy)propionate 
• 1346017-93-3 3-(2-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)ethoxy)propionyl chloride 
• 1346017-85-3 3-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)propionic acid 
• 1346017-83-1 ethyl 3-(4-((4-trifluoromethoxy)phenoxy)piperidin-1-yl)propionate 

Relevant articles and documents

Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6

Well-characterized selective inhibitors of protein arginine methyltransferases (PRMTs) are invaluable chemical tools for testing biological and therapeutic hypotheses. Based on 4, a fragment-like inhibitor of type I PRMTs, we conducted structure-activity

(6,7-DIHYDRO-2-NITRO-5H-IMIDAZOL[2,1-B][1,3]OXAZIN-6YL) AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

(6,7-Dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)amide compounds of formula (I), and their pharmaceutically acceptable salts, preparation methods and pharmaceutical compositions thereof are disclosed, wherein m and R are defined as in the descriptio

ARYL CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS FOR TREATMENT OF PAIN

The present invention provides compounds that are inhibitors of voltage-gated sodium channels (Nav), in particular Nav 1.7, and are therefore useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.