288249-36-5

Upstream product

• 85290-77-3 1,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 16588-02-6 4-chloro-3-cyanonitrobenzene 
• 288251-79-6 2-(4-hydroxypiperidin-1-yl)-5-nitrobenzonitrile 
• 288252-70-0 1-benzotriazole 1,5-dimethylpyrazole-4-carboxylate 
• 288251-78-5 5-amino-2-(4-hydroxypiperidin-1-yl)benzonitrile 
• 31728-75-3 1,5-dimethylpyrazole-4-carboxylic acid 
• 16588-15-1 2-chloro-5-nitro-benzamide 
• 108-30-5 succinic acid anhydride 

Relevant academic research and scientific papers

AMIDE COMPOUNDS AND MEDICINAL USE THEREOF

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.