288588-24-9Relevant articles and documents
Photoactive electron donor-acceptor complex platform for Ni-mediated C(sp3)-C(sp2) bond formation
Kammer, Lisa Marie,Badir, Shorouk O.,Hu, Ren-Ming,Molander, Gary A.
, p. 5450 - 5457 (2021/05/05)
A dual photochemical/nickel-mediated decarboxylative strategy for the assembly of C(sp3)-C(sp2) linkages is disclosed. Under light irradiation at 390 nm, commercially available and inexpensive Hantzsch ester (HE) functions as a potent organic photoreductant to deliver catalytically active Ni(0) species through single-electron transfer (SET) manifolds. As part of its dual role, the Hantzsch ester effects a decarboxylative-based radical generation through electron donor-acceptor (EDA) complex activation. This homogeneous, net-reductive platform bypasses the need for exogenous photocatalysts, stoichiometric metal reductants, and additives. Under this cross-electrophile paradigm, the coupling of diverse C(sp3)-centered radical architectures (including primary, secondary, stabilized benzylic, α-oxy, and α-amino systems) with (hetero)aryl bromides has been accomplished. The protocol proceeds under mild reaction conditions in the presence of sensitive functional groups and pharmaceutically relevant cores.
Electrochemically Promoted Nickel-Catalyzed Carbon-Sulfur Bond Formation
Wang, Yang,Deng, Lingling,Wang, Xiaochen,Wu, Zhengguang,Wang, Yi,Pan, Yi
, p. 1630 - 1634 (2019/03/08)
This work describes a nickel-catalyzed Ullmann-type thiolation of aryl iodidesunder mild electrochemical conditions. The simple undivided cell with graphene/nickel foam electrode setups offers excellent substrate tolerance, affording aryl and alkyl sulfides in good chemical yields. Furthermore, the mechanism for this electrochemical cross-coupling reaction has been investigated by cyclic voltammetry.
CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION
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Page/Page column 33-35, (2018/09/28)
The present invention refers to a process for a catalytic aryl transfer to rearrange the backbone of aromatic C-X bonds.
