289714-02-9

Usage

Uses

Used in Pharmaceutical Industry:
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]pentanamide is used as a therapeutic agent for targeting specific biological pathways. Its unique structure allows it to interact with cellular receptors or enzymes, modulating their activity and potentially leading to therapeutic effects in various diseases.
Used in Drug Delivery Systems:
In the field of drug delivery, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]pentanamide can be used as a carrier molecule to improve the bioavailability and targeting of therapeutic agents. The PEG chain and hydroxyl group can be utilized to conjugate with drugs or other biomolecules, enhancing their solubility, stability, and cellular uptake.
Used in Diagnostic Applications:
Due to its specific interactions with biological systems, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]pentanamide can also be employed in the development of diagnostic tools. It may be used as a molecular probe to detect or image specific biological targets, contributing to the early diagnosis and monitoring of diseases.
Used in Research and Development:
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]pentanamide can serve as a valuable research tool for studying the structure-activity relationships of various biologically active molecules. It can be used to develop new drugs or optimize existing ones, leading to improved therapeutic options for patients.
Used in Cosmetic Industry:
In the cosmetic industry, this molecule could potentially be used as an active ingredient in skincare products, targeting specific skin conditions or promoting overall skin health due to its interactions with biological systems.

Upstream product

• 6338-55-2 2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol 
• 33755-53-2 D-(+)-biotin 2-nitrophenyl ester 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 77544-68-4 8-tosyloxy-3,6-dioxaoctanol 
• 120550-35-8 biotin pentafluorophenyl ester 
• 58-85-5 biotin 
• 139115-92-7 tert-butyl 2-(2-(2-hydroxyethoxy)ethoxy)ethylcarbamate 
• 86520-52-7 2-[2-(2-azidoethoxy)ethoxy]ethanol 

Relevant academic research and scientific papers

MERTK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Thermoresponsive dendronized copolymers for protein recognitions based on biotin–avidin interaction

Thermoresponsive biotinylated dendronized copolymers carrying dendritic oligoethylene glycol (OEG) pendants were prepared via free radical polymerization, and their protein recognitions based on biotin–avidin interaction investigated. Both first (PG1) and second generation (PG2) dendronized copolymers were designed to examine possible thickness effects on the interaction between biotin and avidin. Inherited from the outstanding thermoresponsive properties from OEG dendrons, these biotinylated cylindrical copolymers show characteristic thermoresponsive behavior which provides an envelope to capture avidin through switching temperatures above or below their phase transition temperatures (Tcps). Thus, the recognition of polymer-supported biotin with avidin was investigated with UV/vis spectroscopy and dynamic laser light scattering. In contrast to the case for PG1, the increased thickness for copolymer PG2 hinders partially and inhibits the recognition of biotin moieties with avidin either below or above its Tcp. This demonstrates the significant architecture effects from dendronized polymers on the biotin moieties to shift onto periphery of the collapsed aggregates, which should be a prerequisite for protein recognition. These kinds of novel thermoresponsive copolymers may pave a way for the interesting biological applications in areas such as reversible activity control of enzyme or proteins, and for controlled delivery of drugs or genes.

Design and synthesis of a novel photoaffinity taxoid as a potential probe for the study of paclitaxel-microtubules interactions

A novel and non-radioactive bifunctional photoaffinity probe (BPP) for the study of paclitaxel-microtubules interactions is designed and synthesized. This new BPP-taxoid bears a 3-nitro-5-trifluoromethyl- diazirinyl-phenoxyacetyl group at C-3'N for photoaffinity/photocleavage and a biotin subunit at C-7 for affinity chromatography. (C) 2000 Elsevier Science Ltd.