2899-95-8 Usage
General Description
20-hydroxycortisol is a metabolite of cortisol, a steroid hormone involved in regulating metabolism, immune function, and stress response. It is produced through the conversion of cortisol by the enzyme 11β-hydroxysteroid dehydrogenase type 2 in the kidney. 20-hydroxycortisol is excreted in the urine and can be measured as a marker of cortisol metabolism and adrenal function. Abnormal levels of 20-hydroxycortisol may be associated with conditions such as Cushing's syndrome, adrenal insufficiency, and hypertension. Additionally, it has been studied as a potential biomarker for metabolic disorders and cardiovascular disease.
Check Digit Verification of cas no
The CAS Registry Mumber 2899-95-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,9 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2899-95:
(6*2)+(5*8)+(4*9)+(3*9)+(2*9)+(1*5)=138
138 % 10 = 8
So 2899-95-8 is a valid CAS Registry Number.
2899-95-8Relevant articles and documents
Biotransformation of hydrocortisone by a natural isolate of Nostoc muscorum
Yazdi, Mojtaba Tabatabaei,Arabi, Homeira,Faramarzi, Mohammad Ali,Ghasemi, Younes,Amini, Mohsen,Shokravi, Shadman,Mohseni, Farzaneh Aziz
, p. 2205 - 2209 (2007/10/03)
Hydrocortisone was converted in the culture of an isolated strain of the cyanobacterium Nostoc muscorum PTCC 1636 into some androstane and pregnane derivatives. The microorganism was isolated during a screening program from soil samples collected from paddy fields of north of Iran. The bioproducts obtained were purified using chromatographic methods and identified as 11β-hydroxytestosterone, 11β-hydroxyandrost-4-en-3,17-dione and 11β,17α,20β,21-tetrahydroxypregn-4-en-3-one on the basis of their spectroscopic features.
