28995-21-3Relevant articles and documents
Synthesis of the antimalarial drug FR900098 utilizing the nitroso-ene reaction
Fokin, Andrey A.,Yurchenko, Alexander G.,Rodionov, Vladimir N.,Gunchenko, Pavel A.,Yurchenko, Raisa I.,Reichenberg, Armin,Wiesner, Jochen,Hintz, Martin,Jomaa, Hassan,Schreiner, Peter R.
, p. 4379 - 4382 (2007)
The antimalarial drug FR900098 was prepared from diethyl allylphosphonate involving the nitroso-ene reaction with nitrosocarbonyl methane as the key step followed by hydrogenation and dealkylation. The utilization of dibenzyl allylphosphonate as the start