2901-77-1

Usage

Uses

Used in Dietary Supplements:
N-Acetyl-DL-tyrosine is used as a cognitive enhancer for its role in increasing the production of neurotransmitters, which are essential for brain function and mood regulation.
Used in Pharmaceutical Industry:
N-Acetyl-DL-tyrosine is used as a treatment for phenylketonuria, a metabolic disorder characterized by the inability to break down the amino acid phenylalanine, thereby helping to manage the condition effectively.
Used in Nootropic Supplements:
N-Acetyl-DL-tyrosine is used as a key ingredient in nootropic formulations aimed at improving cognitive performance, enhancing mood, and reducing stress levels, making it popular among individuals seeking to optimize brain health and mental well-being.

Upstream product

• 38243-39-9 α-acetylamino-4-hydroxy-cinnamic acid 
• 34081-17-9 tyrosine ethyl ester 
• 108-24-7 acetic anhydride 
• 23525-90-8 2-acetylamino-3-(4-hydroxyphenyl)propionic acid methyl ester 
• 537-55-3 N-acetyl-L-tyrosine 
• 556-02-5 ?Tyr 
• 10387-40-3 potassium thioacetate 
• 60-18-4 L-tyrosine 

Downstream Products

• 1268157-49-8 N-acetyl-N'-[3-(2-oxotetrahydropyrimidin-1(2H)-yl)propyl]-O-phosphono-D,L-tyrosinamide 
• 537-55-3 N-acetyl-L-tyrosine 
• 60-18-4 L-tyrosine 

Relevant academic research and scientific papers

Potassium Thioacids Mediated Selective Amide and Peptide Constructions Enabled by Visible Light Photoredox Catalysis

A remarkable visible-light-promoted photoredox catalytic methodology involved with amines and eco-friendly potassium thioacids for amide formation was uncovered. This approach can mimic the natural coenzyme acetyl-CoA to selectively acylate amines without affecting other functional groups such as alcohols, phenols, esters, among others. The developed strategy may hold great potential for a comprehensive display of biologically interesting peptide synthesis and amino acid modification through a diacyl disulfide intermediate.

Selectivity in Carbonic Anhydrase Catalyzed Hydrolysis of Standard N-Acetyl-DL-amino Acid Methyl Esters

Carbonic anhydrase-catalyzed hydrolysis of some standard N-acetyl-DL-amino acid methyl esters proceeds with high enantioselectivity.This enzyme hydrolyses selectively D amino acid derivatives in contrast to proteases which have a L stereoselectivity. Key Words: carbonic anhydrase, hydrolysis, N-acetyl-DL-amino acid methyl esters, enantioselectivity.

Racemization of Optically Active Aromatic N-Acetylamino Acids and Asymmetric Transformation of N-Acetyl-2-(4-hydroxyphenyl)glycine via Salt Formation with Optically Active α-Methylbenzylamine

The racemization rates of N-acetyl-(S)-tyrosine, N-acetyl-(S)-phenylalanine, N-acetyl-(R)-2-(4-hydroxyphenyl)glycine , N-acetyl-(R)-2-phenylglycine, and N-acetyl-(S)-alanine were measured by use of (RS)-α-methylbenzylamine as base-catalyst.The first-order rate constant for racemization tended to increase with an increase in the polar substituent constant of the N-acetylamino acid side chain.The racemization appeared to be subject to the inductive effect by the side chain.An asymmetric transformation of (RS)-AcHpg by using (R)-MBA, based on the result of racemization, gave an optically pure salt of (R)-AcHpg with (R)-MBA by successive use of the filtrate as the solvent.Optically pure (R)-2-(4-hydroxyphenyl)glycine was separated from the salt in 87-90percent yield based on the starting (RS)-AcHpg.In addition, the asymmetric transformation of (R)-AcHpg was achieved by using (S)-MBA to give optically pure (S)-Hpg in 80percent yield after purification of the salt of (S)-AcHpg with (S)-MBA followed by hydrolysis.

Cosmetic sunscreen product for the face and body

Cosmetic sunscreen products which contain a tyrosine derivative of the formula: STR1 in which R1 is H or CH3 --(CH2)x, with X being 1 to 20, and R2 is CH3 CO-- or CH3 --(CH2)y --CO, with Y being 1 to 20, provide a long lasting and dark, natural tan after a short exposure to sunlight. The sunscreen product may contain an activator which is an alkali metal or alkaline earth metal salt of adenosine-5'-tri-, di-, or monophosphoric acid and mixtures thereof with an alkali metal or alkaline earth metal hydrogen phosphate.