23525-90-8

Basic information

• Product Name: Tyrosine, N-acetyl-, methyl ester
• Synonyms: 2-acetylamino-3-(4-hydroxy-phenyl)-propionic acid methyl ester;N-Acetyltyrosinmethylester;N-acetyltyrosine methyl ester;N-ACETYL-DL-TYROSINE METHYL ESTER;methyl N-acetyl-tyrosinate;N-acetyl tyrosine methyl ester;methyl 2-acetamido-3-(4-hydroxyphenyl)propanoate
• CAS NO: 23525-90-8
• Molecular Formula: C12H15NO4
• Molecular Weight: 237.255
• Mol File: 23525-90-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 457.0±35.0 °C(Predicted)
• Density: 1?+-.0.06 g/cm3(Predicted)
• CAS DataBase Reference: Tyrosine, N-acetyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Tyrosine, N-acetyl-, methyl ester(23525-90-8)
• EPA Substance Registry System: Tyrosine, N-acetyl-, methyl ester(23525-90-8)

Safety Data

• Hazardous Substances Data: 23525-90-8(Hazardous Substances Data)

Upstream product

• 128459-09-6 N-acetyl-N-methoxyacetamide 
• 1080-06-4 L-Tyr-OCH₃ 
• 1080-06-4 tyrosine methyl ester 
• 75-36-5 acetyl chloride 

Downstream Products

• 2901-77-1 N-acetyltyrosine 
• 537-55-3 N-acetyl-L-tyrosine 
• 19764-32-0 Ac-D-Tyrosine 
• 312689-52-4 C₁₉H₂₄N₂O₃ 
• 90699-92-6 P(C₂H₅)3AuOC₆H₄CH₂CH(NHCOCH₃)CO₂CH₃ 
• 65160-71-6 methyl (2R)-2-acetamido-3-(4-hydroxyphenyl)propanoate 
• 128070-15-5 methyl 2-acetamido-3-(3-fluoro-4-hydroxyphenyl)propanoate 

Relevant articles and documents

Photoinduced Vitamin B12-Catalysis for Deprotection of (Allyloxy)arenes

Vitamin B12 is a natural cobalt complex that, while reduced to the "supernucleophilic" Co(I) form, can easily react with electrophiles via an SN2 mechanism. It is also shown to react via an SN2′ mechanism with allylic compounds allowing for photochemical deprotection of (allyloxy)arenes. A sustainable alternative to commonly used noble metal-catalyzed deprotection reactions is presented.

INTERMEDIATE COMPOUND WHICH IS USED FOR THE PREPARATION OF PIOGLITAZONE

The present invention relates to a novel compound of formula (IV) which is an intermediate that can be used for the preparation of pioglitazone. It also relates to a method of obtaining the novel compound (IV) starting from the natural product L-tyrosine, in which the amino group is protected in the form of aromatic imino group, and a method of obtaining pioglitazone from the said intermediate.

N-METHOXYDIACETAMIDE: A NEW SELECTIVE ACETYLATING AGENT

A simple and efficient method for the direct chemoselective acetylation of primary amines in the presence of alcohols or secondary amines using a new reagent N-methoxydiacetamide is described.