2912-60-9Relevant academic research and scientific papers
Visible light-induced intermolecular radical addition: Facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines
Hu, Bei,Chen, Haixia,Liu, Yan,Dong, Wuheng,Ren, Kai,Xie, Xiaomin,Xu, Hao,Zhang, Zhaoguo
supporting information, p. 13547 - 13550 (2015/01/09)
A highly efficient addition of alkyl α-bromocarboxylates to enamines by visible light-induced photoredox catalysis is reported. Compared with traditional methods, the reaction described here provided an alternative route for the construction of valuable γ-ketoesters in generally good yields.
Azole derivatives as histamine H3 receptor antagonists, Part I: Thiazol-2-yl ethers
Walter,Von Coburg,Isensee,Sander,Ligneau,Camelin,Schwartz,Stark
supporting information; experimental part, p. 5879 - 5882 (2010/11/18)
Most human histamine H3 receptor (hH3R) antagonists follow a general structural blueprint, containing a basic moiety linked by a spacer to a substituted core element. In this investigation the acceptance of thiazol-2-yl ether moieties in the core region is proved with some ether derivatives showing hH3R binding affinities in the nanomolar concentration range. A diversity of structural motifs is used as substituents to enhance the in vitro hH3R binding affinity.
Liquid-phase oxidation of bromovinyl compounds with molecular oxygen
Bayatyan,Bayatyan,Saakyan
, p. 1849 - 1852 (2008/02/08)
Liquid-phase oxidation of bromovinyl compounds with the aim to obtain the corresponding α-bromo acids was studied.
Diastereoselective Synthesis of α-Bromo amides leading to Diastereomerically Enriched α-Amino-, α-Hydroxy- and α-Thiocarboxylic Acid Derivatives
Ward, Robert S.,Pelter, Andrew,Goubet, Dominique,Pritchard, Martyn C.
, p. 469 - 498 (2007/10/02)
α-Bromo amides derived from Oppolzer's camphorsultam can be prepared diastereoselectively starting from racemic α-bromo acids, and undergo epimerisation under appriopriate conditions leading to an enhanced d.e..By reacting the individual isomers or the mi
