291279-14-6Relevant academic research and scientific papers
A family of extended heterocyclic oligomers with thienylene/thiazolylene vinylene cores and triphenylamino/carbazolyl terminals
Xi, Bin,Wang, Na,Ma, Bin-Bin,Tao, Tao,Huang, Wei
, p. 3966 - 3975 (2015)
A series of semiconducting thienylene/thiazolylene vinylene oligomers with triphenylamino/carbazolyl terminal groups have been designed and prepared successfully. Synthetic, structural, thermal, spectral and electrochemical comparisons have been carried out for related compounds. The photophysical results demonstrate that all the vinylene oligomers and their precursors show high luminescence quantum yields. In addition, X-ray single-crystal structure analysis of a typical thiophene based double-bond compound 7 indicates a molecular length of 2.72 nm with the E-configuration.
A Mitochondria-Specific Orange/Near-Infrared-Emissive Fluorescent Probe for Dual-Imaging of Viscosity and H2O2 in Inflammation and Tumor Models
Fan, Li,Zan, Qi,Wang, Xiaodong,Wang, Shuohang,Zhang, Yuewei,Dong, Wenjuan,Shuang, Shaomin,Dong, Chuan
, p. 1303 - 1309 (2021)
Elucidating the intrinsic relationship between viscosity/H2O2 and mitochondria-associated diseases remains a great challenge owing to the lack of research on multiple diseases models, such as inflammation and malignant tumor models.
Two birds with one stone: a NIR fluorescent probe for mitochondrial protein imaging and its application in photodynamic therapy
Cao, Yu-Yao,Chen, Li-Li,Guo, Long,Qi, Ya-Lin,Wang, Hai-Rong,Yang, Yu-Shun,Yuan, Dan-Dan,Zhu, Hai-Liang
, p. 6068 - 6075 (2021)
Mitochondrial proteins, most of which are encoded in the nucleus and the rest of which are regulated by the mitochondrial genome, play pivotal roles in essential cellular functions. However, fluorescent probes that can be used for monitoring mitochondrial proteins have not yet been widely developed, thereby severely limiting the exploration of the functions of proteins in mitochondria. Towards this end, here we propose a near-infrared (NIR) fluorescence probeMPPto effectively illuminate the dynamic changes in mitochondrial proteins in live cells under oxidative stress, with excellent temporal and spatial resolution. Of particular importance,MPPextends the study of the pharmacology involved in apoptosis induced by anti-cancer drugs (hydroxycamptothecin (HCPT), epirubicin (Epi) and cyclophosphamide (CPA)) for the first time. Furthermore, employing a protein-activatable strategy, this probe could serve as an excellent phototherapeutic agent in photodynamic therapy (PDT). Finally,in vivoexperiments suggest that this versatile probe can be used to image tumors in HeLa tumor-bearing mice for 24 h, which demonstrates that our probe could play a dual role as a robust phototherapeutic and imaging agent.
Significant improvement of optoelectronic and photovoltaic properties by incorporating thiophene in a solution-processable D-A-D modular chromophore
Raynor, Aaron M.,Gupta, Akhil,Plummer, Christopher M.,Jackson, Sam L.,Bilic, Ante,Patil, Hemlata,Sonar, Prashant,Bhosale, Sheshanath V.,Manzhos, Sergei
, p. 21787 - 21801 (2015)
Through the incorporation of a thiophene functionality, a novel solution-processable small organic chromophore was designed, synthesized and characterized for application in bulk-heterojunction solar cells. The new chromophore, (2Z,2′Z)-2,2′-(1,4-phenylen
Tuning the HOMO and LUMO energy levels of organic chromophores for dye sensitized solar cells
Hagberg, Daniel P.,Marinado, Tannia,Karlsson, Karl Martin,Nonomura, Kazuteru,Qin, Peng,Boschloo, Gerrit,Brinck, Tore,Hagfeldt, Anders,Sun, Licheng
, p. 9550 - 9556 (2007)
(Chemical Equation Presented) A series of organic chromophores have been synthesized in order to approach optimal energy level composition in the TiO2-dye-iodide/triiodide system in the dye-sensitized solar cells. HOMO and LUMO energy level tun
Rhodanine dyes for dye-sensitized solar cells: Spectroscopy, energy levels and photovoltaic performance
Marinado, Tannia,Hagberg, Daniel P.,Hedlund, Maria,Edvinsson, Tomas,Johansson, Erik M. J.,Boschloo, Gerrit,Rensmo, Hakan,Brinck, Tore,Sun, Licheng,Hagfeldt, Anders
, p. 133 - 141 (2009)
Three new sensitizers for photoelectrochemical solar cells were synthesized consisting of a triphenylamine donor, a rhodanine-3-acetic acid acceptor and a polyene connection. The conjugation length was systematically increased, which resulted in two effec
Rapid and green synthesis of complementary D-A small molecules for organic photovoltaics
Grolleau, Jérémie,Gohier, Frédéric,Allain, Magali,Legoupy, Stéphanie,Cabanetos, Clément,Frère, Pierre
, p. 322 - 328 (2017)
Two push-pull molecules with close molecular structures have been synthesized through two green steps, direct heteroarylation and Knoevenagel condensation. The electronic properties and the basic bilayer heterojunction solar cells demonstrate that the two
Functionalized Acrylonitriles with Aggregation-Induced Emission: Structure Tuning by Simple Reaction-Condition Variation, Efficient Red Emission, and Two-Photon Bioimaging
Niu, Guangle,Zheng, Xiuli,Zhao, Zheng,Zhang, Haoke,Wang, Jianguo,He, Xuewen,Chen, Yuncong,Shi, Xiujuan,Ma, Chao,Kwok, Ryan T. K.,Lam, Jacky W. Y.,Sung, Herman H. Y.,Williams, Ian D.,Wong, Kam Sing,Wang, Pengfei,Tang, Ben Zhong
, p. 15111 - 15120 (2019)
Acrylonitriles with aggregation-induced emission (AIE) characteristics have been found to show promising applications in two-photon biomedical imaging. Generally, elaborate synthetic efforts are required to achieve different acrylonitriles with distinct functionalities. In this work, we first reported the synthesis of two different group-functionalized AIE-active acrylonitriles (TPAT-AN-XF and 2TPAT-AN) obtained simply by mixing the same reactants at different temperatures using a facile and transition metal-free synthetic method. These two AIE luminogens (AIEgens) exhibit unique properties such as bright red emission in the solid state, large Stokes shift, and large two-photon absorption cross section. Water-soluble nanoparticles (NPs) of 2TPAT-AN were prepared by a nanoprecipitation method. In vitro imaging data show that 2TPAT-AN NPs can selectively stain lysosome in live cells. Besides one-photon imaging, remarkable two-photon imaging of live tumor tissues can be achieved with high resolution and deep tissue penetration. 2TPAT-AN NPs show high biocompatibility and are successfully utilized in in vivo long-term imaging of mouse tumors with a high signal-to-noise ratio. Thus, the present work is anticipated to shed light on the preparation of a library of AIE-active functionalized acrylonitriles with intriguing properties for biomedical applications.
MM quadruple bonds supported by cyanoacrylate ligands. Extending photon harvesting into the near infrared and studies of the MLCT states
Brown-Xu, Samantha E.,Chisholm, Malcolm H.,Durr, Christopher B.,Lewis, Sharlene A.,Naseri, Vesal,Spilker, Thomas F.
, p. 2105 - 2116 (2013)
The compounds trans-M2(TiPB)2(L) 2 and trans-M2(TiPB)2(L′) 2 have been prepared from the reactions between M2(T iPB)4 (TiPB = 2,4,6-triisopropylbenzoate, M = Mo or W) and LH or L′H (～2 equiv.), respectively, where L = O 2CC(CN)CH-C6H4-NPh2 and L′ = O2CC(CN)CH-C4H3S-C6H 4-NPh2. These cyanoacrylate ligands promote intense M 2δ to L or L′ π*-transitions that span the range 550-1100 nm. The two molybdenum complexes have been characterized by single crystal X-ray studies that reveal the extensive L-M2-L or L′-M2-L′ M2δ-ligand π-conjugation. The new compounds have been characterized by electronic structure calculations employing density functional theory (DFT) and time-dependent-DFT, cyclic voltammetry, electronic absorption and steady state emission spectroscopy and femtosecond (fs) and nanosecond (ns) time resolved transient absorption (TA) and fs time-resolved infrared spectroscopy (TRIR). The latter allows the determination of the S1 states as 1MLCT that are delocalized over both L and L′. For molybdenum the T1 states are 3MoMoδδ* whereas for tungsten they are 3MLCT.
Highly Efficient Photosensitizers with Far-Red/Near-Infrared Aggregation-Induced Emission for In Vitro and In Vivo Cancer Theranostics
Wang, Dong,Lee, Michelle M. S.,Shan, Guogang,Kwok, Ryan T. K.,Lam, Jacky W. Y.,Su, Huifang,Cai, Yuchen,Tang, Ben Zhong
, (2018)
Fluorescence-imaging-guided photodynamic therapy has emerged as a promising protocol for cancer theranostics. However, facile preparation of such a theranostic material for simultaneously achieving bright emission with long wavelength, high-performance re
