291535-65-4

Usage

Uses

Used in Oncology:
Shegansu B is used as an anticancer agent for its ability to inhibit the proliferation of various cancer cell lines and induce apoptosis in cancer cells.
Used in Autoimmune Disease Treatment:
Shegansu B is used as a therapeutic agent for autoimmune diseases due to its ability to modulate the immune response.
Used in Inflammation Treatment:
Shegansu B is used as a treatment for inflammatory diseases because of its anti-inflammatory effects.

Upstream product

• 67-56-1 methanol 
• 32507-66-7 isorhapontigenin 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 58605-10-0 methyl 3,5-bis(benzyloxy)benzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 121-33-5 vanillin 
• 900515-78-8 C₂₁H₁₉IO₂ 
• 2309-07-1 Methyl ferulate 
• 530-59-6 trans-3,5-dimethoxy-4-hydroxycinnamic acid 
• 42041-51-0 methyl (E)-sinapate 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 20675-96-1 trans-sinapyl alcohol 
• 458-35-5 coniferal alcohol 

Relevant academic research and scientific papers

Applications of Amurensin H derivatives in treating and prevention liver related diseases

The invention discloses applications of Amurensin H derivatives shown as a formula (I) and (II) and pharmaceutically acceptable salt thereof in the preparation of drugs for treating and/or preventingliver related diseases, and also discloses the preparation method of a compound, and applications of the pharmaceutical composition of the compound in the preparation of the drugs for treating and/orpreventing the liver related diseases.

Biomimetic synthesis of active isorhapontigenin dimers

Synthetic isorhapontigenin was treated with several kinds of inorganic reagents and peroxidase so as to prepare active stilbene dimers. Among them, silver acetate in methanol gave two new isorhapontigenin dimers 4 and 5, together with four known natural stilbene dimers 2, 3, 6, and 7. Their structures and relative configurations were determined on the basis of spectral analysis, and their possible formation mechanisms were discussed, respectively. Compounds 2, 6, and 7 were artificially synthesized for the first time. All the products were evaluated for anti-inflammatory activities.

Isolation and biomimetic synthesis of anti-inflammatory stilbenolignans from Gnetum cleistostachyum

One new stilbenolignan, gnetucleistol F (1), and four known stilbenolignans, gnetofuran A (2), lehmbachol D (3), gnetifolin F (4) and gnetumontanin C (5) were isolated from the lianas of Gnetum cleistostachyum C. Y. CHENG (Gnetaceae). Their structures and relative configurations were determined by means of spectroscopic evidence. Compounds 1, 2, 3 and 4 were synthesized for the first time on the basis of their biogenetic pathway, and their possible biomimetical synthetic mechanisms were discussed. The pharmacological activities of all stilbenolignans have been tested. Among them, 1, 2, 3, 4 and 5 showed moderate inhibitory activities on TNF-α and 1 also showed potent inhibitory activity on malondialdehyde.