291535-65-4

Basic information

• Product Name: shegansu B
• Synonyms: shegansu B;Parvifolol D;rel-(+)-5-[(1E)-2-[(2R,3R)-3-(3,5-Dihydroxyphenyl)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-5-benzofuranyl]ethenyl]-1,3-benzenediol
• CAS NO: 291535-65-4
• Molecular Formula: C30H26O8
• Molecular Weight: 514.52264
• Mol File: 291535-65-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: shegansu B(CAS DataBase Reference)
• NIST Chemistry Reference: shegansu B(291535-65-4)
• EPA Substance Registry System: shegansu B(291535-65-4)

Safety Data

• Hazardous Substances Data: 291535-65-4(Hazardous Substances Data)

Usage

General Description

Shegansu B is a natural product isolated from the roots of Tripterygium wilfordii Hook. f., a medicinal plant that is commonly used in traditional Chinese medicine. It is a diterpenoid compound that has been shown to possess anti-inflammatory, immunosuppressive, and anticancer properties. Shegansu B has been found to inhibit the proliferation of various cancer cell lines and induce apoptosis in cancer cells. It also has potential as a therapeutic agent for autoimmune diseases due to its ability to modulate the immune response. Additionally, Shegansu B has been studied for its anti-inflammatory effects, making it a promising candidate for the treatment of inflammatory diseases. Overall, Shegansu B has shown therapeutic potential in the fields of oncology, immunology, and inflammation.

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Relevant articles and documents

Applications of Amurensin H derivatives in treating and prevention liver related diseases

The invention discloses applications of Amurensin H derivatives shown as a formula (I) and (II) and pharmaceutically acceptable salt thereof in the preparation of drugs for treating and/or preventingliver related diseases, and also discloses the preparation method of a compound, and applications of the pharmaceutical composition of the compound in the preparation of the drugs for treating and/orpreventing the liver related diseases.

Isolation and biomimetic synthesis of anti-inflammatory stilbenolignans from Gnetum cleistostachyum

One new stilbenolignan, gnetucleistol F (1), and four known stilbenolignans, gnetofuran A (2), lehmbachol D (3), gnetifolin F (4) and gnetumontanin C (5) were isolated from the lianas of Gnetum cleistostachyum C. Y. CHENG (Gnetaceae). Their structures and relative configurations were determined by means of spectroscopic evidence. Compounds 1, 2, 3 and 4 were synthesized for the first time on the basis of their biogenetic pathway, and their possible biomimetical synthetic mechanisms were discussed. The pharmacological activities of all stilbenolignans have been tested. Among them, 1, 2, 3, 4 and 5 showed moderate inhibitory activities on TNF-α and 1 also showed potent inhibitory activity on malondialdehyde.