291544-98-4

Basic information

• Product Name: 2-(8-Azaspiro[4.5]dec-8-yl)benzophenon
• Synonyms: 2-(8-Azaspiro[4.5]dec-8-yl)benzophenon
• CAS NO: 291544-98-4
• Molecular Weight: 319.447
• Mol File: 291544-98-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(8-Azaspiro[4.5]dec-8-yl)benzophenon(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(8-Azaspiro[4.5]dec-8-yl)benzophenon(291544-98-4)
• EPA Substance Registry System: 2-(8-Azaspiro[4.5]dec-8-yl)benzophenon(291544-98-4)

Safety Data

• Hazardous Substances Data: 291544-98-4(Hazardous Substances Data)

Upstream product

• 176-64-7 8-azaspiro[4.5]decane 
• 342-24-5 o-fluorobenzophenone 

Downstream Products

• 291544-76-8 α-[2-(8-Azaspiro[4.5]dec-8-yl)phenyl]benzylalkohol 

Relevant articles and documents

Preparation and Atropisomerism of 1-(2-Aryl)-piperidin-2-ones

Course and rate of the dehydrogenation of N-tertiary piperidines dependent on their substitution in 4-position and on the hydroxy bearing neighbor group were examined, using mercury(II)-EDTA and the model amino alcohols 1a-1e, 3a-3f, 8a-8f and 10a-10f. The results showed that increasing size of 4-substituents and neighbor groups too decreased the rate of reaction. The products from the 2-substituted benzylic alcohols, the 2-piperidones 7a-7g, 9a-9g and 11a-11g demonstrated atropisomerism. In the case of chiral neighbor groups diastereomeric mixtures were formed.