2916-14-5Relevant academic research and scientific papers
Synthesis of 1,4,5,6-tetrachloro-7,7-dimethoxybicyclo[2.2.1]hept-5- enylmethyl haloacetates
Kyazymova,Mamedbeili,Abdiev,Nagiev,Alieva,Nagiev
, p. 102 - 106 (2009)
The possibility of preparing 1,4,5,6-tetrachloro-7,7-dimethoxybicyclo[2.2. 1]hept-5-enylmethyl haloacetates by the reaction of tetrachlorodimethoxycyclopentadiene with allyl haloacetates was examined. The effect of various factors on the product yield was studied, and the optimal synthesis conditions were found.
Microwave-assisted preparation of benzo[b]furans under solventless phase-transfer catalytic conditions
Bogdal, Dariusz,Warzala, Marek
, p. 8769 - 8773 (2000)
Condensation of salicylaldehyde and its derivatives with various esters of chloroacetic acids in the presence of tetrabutylammonium bromide (TBAB) leads to the synthesis of benzo[b]furans by a solventless phase-transfer catalytic (PTC) reaction under microwave irradiation. (C) 2000 Elsevier Science Ltd.
Allyl amyl glycolate preparation method
-
Paragraph 0024; 0026; 0027; 0028, (2018/11/04)
The invention provides an allyl amyl glycolate preparation method, wherein specifically a reaction is performed by replacing the conventional allyl alcohol with vinyl chloride to prepare allyl amyl glycolate. According to the present invention, the method has advantages of simple operation, high yield, high purity, greatly reduced production cost, reduced waste generation and reduced environmentalhazard, wherein the excess vinyl chloride residue in the final product cannot be generated.
Synthesis method of N-Fmoc (fluorenylmethoxycarbonyl) ethylenediamine propylene acetate hydrochloride
-
Paragraph 0018; 0021, (2018/09/08)
The invention discloses a synthesis method of N-Fmoc (fluorenylmethoxycarbonyl) ethylenediamine propylene acetate hydrochloride. Particularly, chloroacetic acid, ethylenediamine, allyl alcohol, THF (tetrahydrofuran), Fmoc-osu, N-methylmorpholine, ethyl acetate, isopropyl alcohol and methyl tert-butyl ether are taken as raw materials and subjected to an ammonization reaction, a salification reaction, an esterification reaction and an Fmoc protection reaction. The synthesis method of N-Fmoc (fluorenylmethoxycarbonyl) ethylenediamine propylene acetate hydrochloride is high in yield, low in cost,high in product purity and suitable for industrialization and facilitates aftertreatment.
Synthesis of unsaturated esters via highly efficient esterification catalyzed by polymer grafted quarternary ammonium salts as triphase catalysts
Liang, Zheng Yong,Wang, Li Li,Liu, Hui,Huang, Jin Shuo
, p. 1558 - 1561 (2013/09/12)
A series of unsaturated esters were prepared via condensation of sodium carboxylates and alkenyl halide under the condition of macroporous polystyrene grafted quarternary ammonium salt as recyclable phase transfer catalyst, NaI as co-catalyst, Cu powder as inhibitor and H2O as solvent. Under optimal conditions, products yields are 78.2～ 96.0%. The catalyst can be convenient recycled and reutilized for about five times without losing its activity obviously.
Synthesis of bicyclo[2.2.1]hept-5-enyl methyl esters of haloacetic acids
Kyazimova,Mamedbeili,Nagiev,Suleimanova,Khalilov
experimental part, p. 1803 - 1807 (2009/09/08)
Synthesis of norbornenyl methyl esters of a number of haloacetic acids via [4+2] cycloaddition of cyclopentadiene to allyl esters of these acids was examined. The yield and isomer composition of the synthesized compounds were examined in relation to the reaction conditions, and the best conditions for their preparation were found.
Functionalized ozonides by substitution reactions of chlorinated ozonides with difunctional alcohols
Griesbaum, Karl,Quinkert, Ralf-Olaf
, p. 2581 - 2585 (2007/10/03)
Substitution of 3-chloro-3,5-bis(chloromethyl)-5-methyl-1,2,4-trioxolane (3) with allyl alcohol gave the corresponding diastereomeric allyloxy-substituted ozonides 4, which were converted into diozonides 7 by ozone treatment. Substitutions of 3 with ethanediol or with 1,3-propanediol gave the corresponding hydroxyalkoxy-substituted ozonides 8, 14, which were oxidized to the corresponding aldehydes 10, 16. Reaction of 3,5-dichloro-3,5-bis(chloromethyl)-1,2,4-trioxolane (1a) with ethanediol gave the corresponding bis(hydroxy)-substituted ozonide 19 as well as a bicyclic ozonide 18 by reaction of 1a with ethanediol in a ratio of 1:1. Wiley-VCH Verlag GmbH, 1997.
Competitive reactivity as a probe for reaction coordinates in gas-phase ion-molecule chemistry
Holman, Robert W.,Sumpter, Terry L.,Farrar, John,Weigel, Kurt,Bartmess, John E.
, p. 585 - 589 (2007/10/03)
Using the method of competitive reactivity of two functional groups in the same molecule, anionic elimination reactions show considerable kinetic selectivity for small differences in leaving group thermochemistry, in structures of the general type YCH2CH2CH2Z, where Y and Z are good anionic leaving groups.
Effect of Temperature on Atom Transfer Cyclization Reactions of Allylic α-Iodo Esters and Amides
Curran, Dennis P.,Tamine, John
, p. 2746 - 2750 (2007/10/02)
Atom-transfer cyclizations of allyl iodoacetates and N-allyl-N-methyliodoacetamides are much more efficient at 80 deg C than at 25 deg C.At 80 deg C, β-(iodomethyl) lactones and lactams are formed rapidly and in good yield under standard atom-transfer conditions (sunlamp irradiation of iodide and 10percent hexabutylditin in benzene for 10-60 min).It is proposed that this temperature effect is responsible for some unusual observations by Jolly and Livinghouse in the cyclization of N-cyclohexenyl-N-methyliodoacetamide.The results suggest that the beneficial effect of temperature arises because an increase in the rate of rotation of t he OC-O or OC-N bond in the intermediate radicals begins to convert syn radicals (which cannot cyclize) to anti radicals (which can cyclize).Consistent with this hypothesis, the radical derived from N,N-diallyliodoacetamide (which always has a favorable arrangement for cyclization) closes with excellent efficiency at 25 deg C.
THE NITROGENATED ALLYLIC SYSTEM AS AN INTRAMOLECULAR NUCLEOPHILE: A NEW ROUTE TO PYRAZOLES
Momose, Takefumi,Toyooka, Naoki,Ikuta, Takashi,Yanagino, Hironobu
, p. 789 - 793 (2007/10/02)
A new route to pyrazoles via the cyclization of N-allyl-N-nitrosoamides is described.
