29193-67-7Relevant academic research and scientific papers
Oxidative cleavage of alkenes using an in situ generated iodonium ion with oxone as a terminal oxidant
Thottumkara, Prem P.,Vinod, Thottumkara K.
supporting information; experimental part, p. 5640 - 5643 (2011/02/27)
A facile and operationally convenient catalytic procedure for oxidative cleavage of alkenes is described. In situ formed [hydroxy(4-carboxyphenyl) iodonium]ion, 2, from the oxidation of 4-iodobenzoic acid, 1, has been shown to facilitate the cleavage of a variety of alkenes in presence of Oxone as a co-oxidant. Optimization of the reaction conditions using 1-phenyl-1- cyclohexene, 3, and the competitive oxidative cleavage of different substrates using the optimized conditions has uncovered important mechanistic details of the reaction.
