29304-63-0Relevant articles and documents
The effect of PEGylated dendrimers on the catalytic activity and stability of palladium particles in the suzuki reaction
Gaebler, Christian,Jeschke, Janine,Nurgazina, Gulnar,Dietrich, Sascha,Schaarschmidt, Dieter,Georgi, Colin,Schlesinger, Maik,Mehring, Michael,Lang, Heinrich
, p. 317 - 323 (2013)
Stable dendrimer-coated Pd particles were synthesized using the wet-chemical borohydride reduction method of Pd(II) salts in the presence of low-generation (poly)ethylene glycol-terminated amidoamine-based dendrimers. The identity and structure of the Pd-
MeOTf-catalyzed formal [4?+?2] annulations of styrene oxides with alkynes leading to polysubstituted naphthalenes through sequential electrophilic cyclization/ring expansion
Chen, Chao,Xi, Chanjuan,Zhang, Zeyu,Zou, Song
supporting information, (2021/12/30)
MeOTf-catalyzed formal [4 + 2] annulation of styrene oxides with alkynes to afford polysubstituted naphthalenes has been realized, which undergoes sequential electrophilic cyclization/ring expansion. A range of substrates were tolerated in the formation of naphthalene derivatives with high regioselectivity in satisfactory yields. The reaction could also be carried out on gram scale.
Monosubstituted, Anionic Imidazolyl Ligands from N?H NHC Precursors and Their Activity in Pd-Catalyzed Cross-Coupling Reactions
Clark, Kyle J.,Ess, Daniel H.,Jensen, Christopher A.,Kenney, Karissa C.,Larson, Alexandra J. S.,Martinez, Erin E.,Michaelis, David J.,Nazari, S. Hadi,Smith, Stacey J.,Valdivia-Berroeta, Gabriel A.
supporting information, (2020/07/06)
We report that treatment of several 2-diphenylphosphinoimidazoles with Pd(II) salts generates monosubstituted N?H NHC?Pd complexes via insertion into the C?P bond. Removal of the N?H proton in situ leads to anionic (X-type) or imidazolyl-Pd complexes that are highly stable and catalytically active, achieving up to 340,000 turnovers at 1 ppm catalyst loading in Suzuki-Miyaura reactions. DFT-calculated Tolman electronic parameters for the sterically small ligands suggest that these ligands are significantly more donating than traditional NHCs, which provides a rationale for rapid cross-coupling catalysis. Excellent reactivity is also demonstrated in Sonogashira reactions. (Figure presented.).
Preparation method of aromatics methylation
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Paragraph 0084; 0085; 0086, (2019/11/20)
The invention relates to the technical field of organic synthesis or pharmaceutical chemistry, in particular to a preparation method of aromatics methylation. Under inert gas protection, a substrate A, a methylation reagent B and a termination agent C are used as starting materials, under the action of a catalyst D, a ligand E, a norborneene derivative G and a base F, the starting materials are subjected to a stirring reaction in an organic solvent H at 30-140 DEG C, and after the reaction, a reaction mixture is sucked and filtered, concentrated and purified to prepare a product of aromatics methylation shown as any formula of a formual I, a formual II and a formual III (please see the specifications for the formual I, the formual II and the formual III). According to the preparation method, related main raw materials are aryl iodide, trimethyl phosphate, methyl sulfonate, deuterated methyl ester sulfoacid, olefin, alkyne, an aryl boron compound, cyanide, bis(pinacolato)diboron and a proton source, the raw materials can be used as a commercial reagent without special treatment, the cost is low, and the variety is great. According to the method, aromatics methylation products can beprepared in large quantities (grams), and a good foundation is laid for industrial production.
