295320-98-8

Upstream product

• 518332-44-0 5-O-tert-butyldimethylsilyl-3-O-[2,6-di-O-benzyl-3,4-O-[(2S,3S)-2,3-dimethoxybutan-2,3-yl]-α-D-glucopyranosyl]-1,2-O-isopropylidene-α-D-ribofuranose 
• 795305-86-1 phenyl 3,4-O-[(2S,3S)-2,3-dimethoxybutan-2,3-yl]-1-thio-β-D-glucopyranoside 
• 795305-88-3 phenyl 2,6-di-O-benzyl-3,4-O-[(2S,3S)-2,3-dimethoxybutan-2,3-yl]-1-thio-β-D-glucopyranoside 
• 176798-33-7 2,2,3,3-tetramethoxybutane 
• 100-39-0 benzyl bromide 
• 32934-24-0 ethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside 
• 7473-36-1 ethyl 1-thio-β-D-glucopyranoside 
• 197644-80-7 (2'S,3'S)-ethyl 2,6-di-O-benzyl-3,4-di-O-(2',3'-dimethoxybutane-2',3'-diyl)-1-thio-β-D-glucopyranoside 
• 197644-79-4 (2'S,3'S)-ethyl 3,4-di-O-(2',3'-dimethoxybutane-2',3'-diyl)-1-thio-β-D-glucopyranoside 
• 190970-10-6 1,2-O-isopropylidene-5-O-tert-butyldiphenylsilyl-α-D-ribofuranose 
• 2936-70-1 (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3,4,5-triol 
• 196868-07-2 1,2-O-isopropylidene-5-O-(tert-butyl)dimethylsilyl-α-D-ribofuranoside 
• 518332-41-7 2,6-di-O-benzyl-3,4-O-[(2S,3S)-2,3-dimethoxybutan-2,3-yl]-1-phenylsulfinyl-β-D-glucopyranoside 
• 197644-81-8 (2S,3S)-3-O-[2',6'-di-O-benzyl-3',4'-di-O-(2,3-dimethoxybutane-2,3-diyl)-α-D-glucopyranosyl]-1,2-O-isopropylidene-5-O-tert-butyldiphenylsilyl-α-D-ribofuranoside 

Downstream Products

• 197644-82-9 (2S,3S)-5-O-benzyl-3-O-[2',6'-di-O-benzyl-3',4'-di-O-(2,3-dimethoxybutane-2,3-diyl)-α-D-glucopyranosyl]-1,2-O-isopropylidene-α-D-ribofuranoside 
• 912567-58-9 3-O-[2,6-di-O-benzyl-3,4-O-[(2S,3S)-2,3-dimethoxybutan-2,3-diyl]-α-D-glucopyranosyl]-5-deoxy-1,2-O-isopropylidene-5-O-trifluoromethanesulfonyl-α-D-ribofuranose 
• 197644-83-0 1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside 
• 1213232-41-7 C₃₇H₅₀O₁₂ 
• 305839-06-9 2'-O-acetyl-3'-O-(3'',4''-di-O-acetyl-2'',6''-di-O-benzyl-α-D-glucopyranosyl)-5'-azido-N⁶-benzoyl-5'-deoxyadenosine 
• 305839-08-1 5'-azido-N⁶-benzoyl-3'-O-(2'',6''-di-O-benzyl-α-D-glucopyranosyl)-5'-deoxyadenosine 
• 518332-48-4 5-deoxy-5-phenyl-3-O-(2,6-di-O-benzyl-3,4-di-O-isobutyryl-α-D-glucopyranosyl)-1,2-O-isobutyryl-α-D-ribofuranose 
• 912567-54-5 C₆₂H₆₄N₅O₁₇P₃ 
• 912567-53-4 C₆₁H₆₂N₅O₁₇P₃ 
• 912567-63-6 C₅₅H₅₇O₁₇P₃ 
• 912567-50-1 N⁶-benzoyl-9-[5-deoxy-3-O-(2,6-di-O-benzyl-3,4-di-O-isobutyryl-α-D-glucopyranosyl)-2-O-isobutyryl-5-phenethyl-β-D-ribofuranosyl]adenine 
• 912567-49-8 N⁶-benzoyl-9-[5-benzyl-5-deoxy-3-O-(2,6-di-O-benzyl-3,4-di-O-isobutyryl-α-D-glucopyranosyl)-2-O-isobutyryl-β-D-ribofuranosyl]adenine 

Relevant academic research and scientific papers

Design and synthesis of indole derivatives of adenophostin A. A entry into subtype-selective IP3 receptor ligands

Indole derivatives 3a and 3b of adenophostin A (2) in which the adenine of 2 was replaced with indole or 4-fluoroindole was designed as potential inositol trisphosphate receptor ligands. These target compounds were successfully synthesized from the key di

Design and synthesis of 5′-deoxy-5′-phenyladenophostin A, a highly potent IP3 receptor ligand

5′-Deoxy-5′-phenyladenophostin A (5), designed as a useful IP3 receptor ligand based on the previous structure-activity relationship studies, was successfully synthesized via two key stereoselective glycosidation steps. This compound proved to

Synthesis of adenophostin A analogues conjugating an aromatic group at the 5′-position as potent IP3 receptor ligands

Previous structure-activity relationship studies of adenophostin A, a potent IP3 receptor agonist, led us to design the novel adenophostin A analogues 5a-c, conjugating an aromatic group at the 5′-position to develop useful IP3 recep

Synthesis of potent agonists of the D-myo-inositol 1,4,5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A

Clustered disaccharide analogues of adenophostin A (2), i.e. mono-, di-, and tetravalent derivatives 6-8, respectively, were synthesized and evaluated as novel ligands for the tetrameric D-myo-inositol 1,4,5-trisphosphate receptor (IP3R). The s

Synthesis of photoaffinity derivatives of adenophostin A

Photoaffinity derivatives 7 and 8 of adenophostin A, modified at the 5'- and 1'-positions, were prepared by a chemoselective reaction of the aminophostins 15 and 30 with N-succini-midyl p-benzoyl-2,3-dihydrocinnamate (p-benzoyldihydrocinnamoyl-N-hydroxysu

Synthesis of clustered disaccharide polyphosphate analogues of adenophostin A

Three new potential ligands for the IP3 receptor (i.e. compounds 5-7) were prepared by Sonogashira coupling of propargyl 2-O-acetyl-5-O-benzyl-3-O-(3,4-di-O-acetyl-2,6-di-O-benzyl-α-D-glucopyranosyl) -β-D-ribofuranoside (15) with iodobenzene, 1,2-diiodobenzene and 1,2,4,5-tetraiodobenzene, followed by deacetylation, phosphorylation and deprotection.