2954-94-1

Usage

Uses

Used in Pharmacology:
Dicyclohexyltin dibromide is used as an inhibitor for pancreatic cancer cell lines. It is particularly effective in suppressing the growth and proliferation of pancreatic cancer cells through its interaction with organotin polyesters. DICYCLOHEXYLTIN DIBROMIDE has shown promise in the development of novel therapeutic strategies for pancreatic cancer treatment.

InChI:InChI=1/2C6H11.2BrH.Sn/c2*1-2-4-6-5-3-1;;;/h2*1H,2-6H2;2*1H;/q;;;;+2/p-2/rC12H22Br2Sn/c13-15(14,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h11-12H,1-10H2

Upstream product

• 1449-55-4 Tetracyclohexyl-stannan 
• 7726-95-6 bromine 
• 3023-92-5 tris(cyclohexyl)tin bromide 
• 542-18-7 cyclohexyl chloride 
• 3342-69-6 dicyclohexyltin dichloride 
• 931-50-0 cyclohexylmagnesium bromide 
• 931-51-1 cyclohexylmagnesiumchloride 

Downstream Products

• 26285-71-2 (C₂H₅)2Sn(cyclo-C₆H₁₁)2 
• 7544-32-3 (cyclo-C₆H₁₁)2Sn(C₈H₁₇)2 
• 5764-59-0 (C₅H₁₁)2Sn(cyclo-C₆H₁₁)2 
• 5764-41-0 (iso-C₅H₁₁)2Sn(cyclo-C₆H₁₁)2 
• 7544-30-1 (cyclo-C₆H₁₁)2Sn(C₆H₁₁)2 
• 7544-31-2 (cyclo-C₆H₁₁)2Sn(C₇H₁₅)2 
• 26285-74-5 (cyclo-C₆H₁₁)2Sn(C₆H₄-p-CH₂CHCH₂)2 
• 7544-33-4 (cyclo-C₆H₁₁)2Sn(C₉H₁₉)2 
• 26285-72-3 (cyclo-C₆H₁₁)2Sn(CH₂CHCH₂)2 
• 6039-62-9 (C₄H₉)2Sn(cyclo-C₆H₁₁)2 
• 26285-76-7 (cyclo-C₆H₁₁)2Sn(C₆H₄-p-Br)2 
• 20204-07-3 (C₆H₅)2Sn(cyclo-C₆H₁₁)2 
• 26367-78-2 (cyclo-C₆H₁₁)2Sn(C₆H₄-p-OCH₃)2 
• 7544-34-5 (cyclo-C₆H₁₁)2Sn(C₁₀H₂₁)2 

Relevant academic research and scientific papers

A novel route for the preparation of dimeric tetraorganodistannoxanes

The reaction of polymeric diorganotin oxides, (R2SnO)n (R = Me, Et, n-Bu, n-Oct, c-Hex, i -Pr, Ph), with saturated aqueous NH4X (X = F, Cl, Br, I, OAc) in refluxing 1,4-dioxane afforded in high yields dimeric tetraorganodistannoxanes, [R2(X)SnOSn(X)R2]2, and in a few cases diorganotin dihalides or diacetates, R2SnX2. The reported method appears suitable for the synthesis of fluorinated tetraorganodistannoxanes. Identification of [R2(OH)SnOSn(X)R2]2 (R=n-Bu; X = Cl, Br) and [R2(OH)SnOSn(X)R2] [R2(X)SnOSn(X)R2] suggest a serial substitution mechanism starting from [R2(OH)SnOSn(OH)R2]2. X-ray crystal structure determinations are reported for [Me2(AcO)SnOSn(OAc)Me2]2 (29a), [i-Pr2(Br)SnOSn(Br)i-Pr2]2 (20a), [c-Hex2 (F)SnOSn(F)c-Hex2]2 (5a) and [c-Hex2(F)SnOSn(Cl)c-Hex2]2 (36), respectively. These show the presence of a central (R2Sn)2O2 core that is connected, via the oxygen atoms, to R2Sn entities. Acetate (29a) or halides (5a, 20a, 36) complete the coordination about the tin centres.

Electrophilic cleavage of tin-alicyclic and tin-aryl bonds involving the synthesis of cyclohexyl-tin, -tellurium and -antimony compounds - Part I

Cyclohexyl-tin, -tellurium and -antimony halides have been obtained in good yields by the electrophilic cleavage of Sn-C bond(s) from symmetrical and unsymmetrical cyclohexyl tins, CynPnPh4-n (n = 1, 2, 4) employing Br2, I2, ICl, IBr, TeCl4 and SbCl5 in CCl4 under mild conditions.