2955-50-2

Usage

Uses

Used in Pharmaceutical Industry:
(2S)-2-amino-3-methyl-butanedioic acid is used as a building block for the development of new drugs for the treatment of various diseases due to its unique structure and potential biological activity.
Used in Organic Chemistry:
(2S)-2-amino-3-methyl-butanedioic acid is used as a synthetic intermediate for the synthesis of more complex molecules, contributing to the advancement of organic chemistry.
Safety:
As with many chemicals, (2S)-2-amino-3-methyl-butanedioic acid should be handled with care and in accordance with proper safety protocols to ensure the safety of users and the environment.

InChI:InChI=1/C5H9NO4/c1-2(4(7)8)3(6)5(9)10/h2-3H,6H2,1H3,(H,7,8)(H,9,10)/t2?,3-/m0/s1

Upstream product

• 535-11-5 Ethyl 2-bromopropionate 
• 90877-70-6 ethyl 2-acetamido-2-cyanoacetate 
• 20268-80-8 diethyl 2-amino-3-methylsuccinate 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 759-65-9 diethyl oxalpropionate 

Downstream Products

• 5380-36-9 (-)-threo-3-Methylaepfelsaeure 
• 5380-37-0 (2S,3S)-2-Hydroxy-3-methyl-succinic acid 
• 86535-06-0 (2R,3S)-threo-3-methylbutane-1,2,3-triol 4-benzyl ether 1-tosylate 
• 86562-36-9 (2R,3R)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-10-6 (2S,3S)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-18-4 2-methyl-3-pentanol (S)-(-)-MTPA ester 
• 86535-19-5 2-methyl-3-pentanol (R)-(+)-MTPA ester 
• 86535-17-3 (2R,3R)-threo-2-methylpentane-1,3-diol 1-tosylate 
• 86535-14-0 (2S,3S)-2-methyl-1-(4-methylbenzenesulfonyloxy)-3-pentanol 
• 86535-08-2 (2S,3S)-threo-2-methylpentane-1,3-diol 1-benzyl ether 3-THP ether 
• 86562-34-7 (2R,3R)-threo-2-methylpentane-1,3-diol 1-benzyl ether 3-THP ether 
• 86535-07-1 (2S,3S)-threo-2-methylpentane-1,3-diol 1-benzyl ether 
• 83997-86-8 serricornin acetate <(4S,6S,7S)-4,6-dimethyl-7-acetoxy-3-nonanone> 
• 13398-40-8 (2R,3R)-threo-β-methylmalic acid 

Relevant academic research and scientific papers

Indium-mediated allylation and Reformatsky reaction on glyoxylic oximes under ultrasound irradiation

A novel and more convenient method for the indium-promoted allylation of glyoxylic oximes based on the use of ultrasonic waves is reported. A similar procedure was used to develop the first example reported in the literature of an indium-mediated Reformatsky reaction on oxime ethers.

Organocatalytic synthesis of β-alkylaspartates via β-lactone ring opening

(Chemical Equation Presented) Cinchona alkaloid-catalyzed reaction of ethyl glyoxylate with substituted ketenes, formed in situ, gives disubstituted β-lactones in moderate yield and high enantiomeric excess. Subsequent azide ring opening, reduction, and e

SYNTHESIS AND ABSOLUTE STEREOCHEMISTRY OF SERRICORNIN

The absolute stereochemistry of serricornin (4,6-dimethyl-7-hydroxy-3-nonanone) was established as 4S, 6S, 7S by synthesizing both (4S, 6S, 7S)-isomer and its antipode.Only the natural enantiomer was bioactive.by