78479-16-0

Upstream product

• 15681-48-8 lithium dimethylcuprate 
• 87172-27-8 cis-4-benzyloxy-2,3-epoxy-1-butanol 
• 1184-53-8 methylcopper 
• 100-39-0 benzyl bromide 
• 57280-24-7 (R)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-propan-1-ol 
• 78479-15-9 (2S,3R)-threo-3-methylbutane-1,2,4-triol 1,2-acetonide 4-benzyl ether 
• 78513-07-2 ((2R,3S)-3-((benzyloxy)methyl)oxiran-2-yl)methanol 
• 67-64-1 acetone 
• 6061-13-8 (2S,3S)-3-methylaspartic acid 
• 642-92-2 D,L-threo-β-methylaspartic acid 
• 50460-80-5 (2S,3S)-2-Hydroxy-3-methyl-bernsteinsaeuredimethylester 
• 117431-90-0 (2R,3S)-4-benzyloxy-2,3-epoxy-1-butyl 3,5-dinitrobenzoate 
• 69743-60-8 (2S,3R)-threo-3-methylbutane-1,2,4-triol 1,2-acetonide 
• 77333-42-7 (2S,3R)-threo-3-methylbutane-1,2,4-triol 

Downstream Products

• 78433-56-4 (R)-2-((S)-2-Benzyloxy-1-methyl-ethyl)-oxirane 
• 95532-13-1 2,2-Dimethyl-propionic acid (2R,3S)-4-benzyloxy-2-hydroxy-3-methyl-butyl ester 
• 81380-11-2 Toluene-4-sulfonic acid (1S,2R)-3-benzyloxy-1-hydroxymethyl-2-methyl-propyl ester 
• 78433-56-4 (R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-oxirane 
• 81380-09-8 [(2S,3R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-3-methyl-tetrahydro-pyran-2-yl]-methanol 
• 81380-09-8 [(2R,3S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-3-methyl-tetrahydro-pyran-2-yl]-methanol 
• 80109-44-0 (2S,3S,6S)-1-Benzyloxy-2-methyl-6-(R)-oxiranyl-heptan-3-ol 
• 80109-44-0 (2S,3R,6S)-1-Benzyloxy-2-methyl-6-(R)-oxiranyl-heptan-3-ol 
• 81380-07-6 (2R,3S,6S)-1-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-heptan-3-ol 
• 81380-07-6 (2S,3S,6S)-1-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-heptan-3-ol 
• 81380-07-6 (2S,3R,6S)-1-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-heptan-3-ol 

Relevant academic research and scientific papers

Synthetic studies on bafilomycin A1: Stereoselective synthesis of the C12-C17 fragment and its coupling with the C 1-C11 subunit

Stereoselective addition of (E)-1-lithio-2-tributylstannylethylene on a chiral cyclic di-t-butylsilyleneketal C14-C17 aldehyde afforded the required Felkin-Anh adduct for the synthesis of the C 12-C17 fragment of bafilomycin A1, the configuration of which was assigned unambiguously. After appropriate coupling with the enantiopure C1-C11 fragment, the C 12-C17 subunit obtained here can be used for the study of the 16-membered macrolide formation either by an acyl activation or an intramolecular Stille reaction. Intermolecular esterification of the 15-OH with an acyl activation of the carboxylic acid of the C1-C11 fragment, in modified Yamaguchi's conditions, affords here an intermediate for examining an intramolecular Stille coupling.

Isomer Selectivity in Stereocontrolled Payne Rearrangement-epoxide Cleavage of 2,3-Epoxy Alcohols in Aprotic Solvents: Application to an Enantioselective Total Synthesis of (+)-exo-Brevicomin

Organo-copper and -cuprate reagents may be used to trap the more reactive epoxy alkoxide isomer in a Lewis acid-catalysed Payne rearrangement process.This methodology has been used as the key step in a five-step enantioselective total synthesis of (+)-exo

A NEW SYNTHESIS OF (-)-Α-MULTISTRIATIN, THE PHEROMONE OF THE SMALLER EUROPEAN ELM BARK BEETLE

(-)-Α-Multistriatinoctane> was synthesized from (Z)-2-butene-1,4-diol monobenzyl ether by employing the sharpless asymmetric epoxidation and the regioselective epoxide cleavage with Me3Al as the k

REGIOSELECTIVITY OF THE REACTIONS OF TRIALKYLALUMINUM REAGENTS WITH 2,3-EPOXYALCOHOLS: APPLICATION TO THE SYNTHESIS OF α-CHIRAL ALDEHYDES

Treatment of optically active 2,3-epoxyalcohols with trialkylaluminum reagents followed by periodate cleavage constitutes a convenient synthesis of α-chiral aldehyde derivatives, especially when the branching alkyl group is methyl.

SYNTHESIS AND ABSOLUTE STEREOCHEMISTRY OF SERRICORNIN

The absolute stereochemistry of serricornin (4,6-dimethyl-7-hydroxy-3-nonanone) was established as 4S, 6S, 7S by synthesizing both (4S, 6S, 7S)-isomer and its antipode.Only the natural enantiomer was bioactive.by

Studies toward polyether antibiotics: stereospecific synthesis of polysubstituted tetrhydropyrans

A stereospecific and general method for the preparartion of trans-tetrahydropyrans 1 and cis-tetrahydropyrans 2 from acyclic precursors are described.Compound 12, a possible intermediate for the synthesis of antibiotic X-14547A, has been synthesized.

DETERMINATION OF THE ABSOLUTE CONFIGURATION AT C-6 AND C-7 SERRICORNIN (4,6-DIMETHYL-7-HYDROXY-3-NONANONE), THE SEX PHEROMONE OF THE CIGARETTE BEETLE

The absolute configuration at C-6 and C-7 of serricornin was established as (6S, 7S) by synthesizing its (6R, 7S)-erythro and (6R, 7R)-threo isomers.