29701-85-7

Upstream product

• 111-85-3 n-chlorooctane 
• 4559-70-0 Diphenylphosphine oxide 
• 629-27-6 1-Iodooctane 
• 111-83-1 1-bromo-octane 
• 111-66-0 oct-1-ene 
• 53121-41-8 octyl phosphorodichloridate 
• 71-43-2 benzene 
• 114768-15-9 octyl(diphenyl)phosphane sulfide 
• 934538-84-8 diphenyl-phosphinothioic acid S-pent-4-ynyl ester 
• 1499-21-4 Diphenylphosphinic chloride 
• 6591-07-7 diphenylphosphane sulfide 
• 829-85-6 diphenylphosphane 
• 124-13-0 Octanal 
• 1079-66-9 chloro-diphenylphosphine 

Relevant academic research and scientific papers

Visible light induced hydrophosphinylation of unactivated alkenes catalyzed by salicylaldehyde

An air and water insensitive visible light induced hydrophosphinylation of unactivated alkenes is reported. A small amount of a simple and cheap compound, salicylaldehyde, is used as a photosensitizer. The reaction is carried out in a basic aqueous solution which enables the deprotonated salicylaldehyde to show visible light absorption.

Photoinduced selective hydrophosphinylation of allylic compounds with diphenylphosphine oxide leading to γ-functionalized P-ligand precursors

A series of bifunctional phosphine compounds promising as γ-functionalized phosphine ligand precursors are conveniently synthesized by the radical addition of diphenylphosphine oxide (Ph2P(O)H) to allylic compounds under photoirradiation. The p

Radical Hydrophosphorylation of Alkynes with R2P(O)H Generating Alkenylphosphine Oxides: Scope and Limitations

Radical hydrophosphorylation of aliphatic terminal alkynes with H-phosphine oxides can produce the corresponding anti-Markovnikov alkenylphosphorus adducts in moderate yields. This method is a cleaner approach for the preparation of the corresponding alke

Phosphinoyl Radical Initiated Vicinal Cyanophosphinoylation of Alkenes

A double-functionalization reaction of alkenes through Mn(OAc)3-mediated phosphinoyl radical addition followed by CuCN-catalyzed cyanation is introduced. This one-pot reaction is performed under mild conditions to afford vicinal cyanophosphinoylation products.

Catalyst- and solvent-free hydrophosphination and multicomponent hydrothiophosphination of alkenes and alkynes

The hydrophosphination of carbon-carbon multiple bonds has been generally performed under acid, base or metal catalysis in different solvents. Herein, alkyl and alkenyl tertiary phosphines are obtained by the addition of diphenylphosphine to alkenes and alkynes, respectively, in the absence of a solvent and a catalyst. In the presence of elemental sulfur, the corresponding alkyl and alkenyl tertiary phosphine sulfides are synthesized in a three-component process. These simple methods, which meet most of the principles of Green Chemistry, are highly regioselective towards the anti-Markovnikov products and diastereoselective towards the Z alkenyl phosphines. The mechanistic aspects of the reactions are also tackled and the efficiency of the latter is compared with that of the catalytic methods.

Solvent-controlled direct radical oxyphosphorylation of styrenes mediated by Manganese(III)

Direct radical oxyphosphorylation of styrenes with diarylphosphine oxides and dialkyl phosphites mediated by Mn(OAc)3 is described. The solvent played a key role in this selective difunctionalization reaction.

A silver-initiated free-radical intermolecular hydrophosphinylation of unactivated alkenes

A scalable, operationally easy intermolecular hydrophosphinylation of various unactivated alkenes with H-P(O) compounds via an Ag(i)-initiated free radical process was developed. Mechanistic studies including electron-spin-resonance (ESR) and radical clock experiments suggest that atom transfer processes were involved in this system.

Direct radical acetoxyphosphorylation of styrenes mediated by manganese(III)

Direct radical acetoxyphosphorylation of styrenes mediated by Mn(OAc)3 with diphenylphosphine oxide and dialkyl phosphites was described, and a new type of difunctionalization of alkenes was achieved.

Ph2PI as a reduction/phosphination reagent: Providing easy access to phosphine oxides

The reaction of aldehydes with Ph2PI provides a facile way to the synthesis of pentavalent phosphine compounds with moderate to good yields.

Photoinduced hydrophosphinylation of alkenes with diphenylphosphine oxide

Photoinduced hydrophosphinylation of alkenes with diphenylphosphine oxide took place regioselectively affording the corresponding phosphine oxide in good yields. This hydrophosphinylation is of simple operation and widely tolerant to a variety of the functionalities.