297173-62-7Relevant articles and documents
syn-Selective boron mediated aldol condensations for the asymmetric synthesis of β-hydroxy-α-amino acids
Caddick,Parr,Pritchard
, p. 5963 - 5966 (2000)
Imidazolidinone-bound glycine enolate derivatives have been shown to undergo aldol condensation with aromatic and aliphatic aldehydes in good yields and with excellent stereocontrol (62-84%, 93-95% d.e.). Removal of the pendant imidazolidinone auxiliary and hydrogenolysis affords the β-hydroxy- α-amino acid derivatives. (C) 2000 Elsevier Science Ltd.