2976-34-3

Basic information

• Product Name: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene
• Synonyms: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene;Methyl 2-nitrophenyl sulphone;Methyl 2-Nitrophenyl Sulfone
• CAS NO: 2976-34-3
• Molecular Formula: C₇H₇NO₄S
• Molecular Weight: 201.19978
• Mol File: 2976-34-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 106 °C
• Boiling Point: 403.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.406±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene(2976-34-3)
• EPA Substance Registry System: 2-(Methylsulphonyl)nitrobenzene, 1-(Methylsulphonyl)-2-nitrobenzene(2976-34-3)

Safety Data

• Hazardous Substances Data: 2976-34-3(Hazardous Substances Data)

Usage

General Description

2-(Methylsulphonyl)nitrobenzene and 1-(Methylsulphonyl)-2-nitrobenzene are both chemical compounds with similar structures. They belong to the class of nitrobenzenes and contain a methylsulphonyl group. These chemicals are commonly used in the production of dyes, pigments, and pharmaceuticals. They are also used in organic synthesis and as intermediates in the manufacturing of other chemicals. Both compounds are known for their potential toxicity and should be handled with caution. Overall, these chemicals have various industrial applications and are important intermediates in the synthesis of other chemical compounds.

Upstream product

• 3058-47-7 methyl 2-nitrophenyl sulfide 
• 27489-27-6 <(2-Nitro-phenyl)sulfonyl>essigsaeure 
• 13165-79-2 2-nitrobenzenesulfinic acid 
• 74-88-4 methyl iodide 
• 3112-85-4 methylphenylsulfonate 
• 2987-53-3 2-(Methylthio)aniline 
• 79-08-3 bromoacetic acid 
• 79-11-8 chloroacetic acid 
• 27489-42-5 2-Methylsulfonylnitrosobenzol 
• 27489-28-7 methyl 2-(2-nitrophenylsulfonyl)acetate 
• 27489-32-3 N-(2-methanesulfonyl-phenyl)-hydroxylamine 
• 100-68-5 methyl-phenyl-thioether 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 577-19-5 2-nitrophenyl bromide 

Downstream Products

• 27489-39-0 bis-(2-methanesulfonyl-phenyl)-diazene-N-oxide 
• 2987-49-7 2-(methylsulfonyl)aniline 
• 27489-32-3 N-(2-methanesulfonyl-phenyl)-hydroxylamine 
• 824-39-5 sodium o-nitrophenate 
• 20628-27-7 N-(2-(methylsulfonyl)phenyl)acetamide 
• 125106-55-0 o-mercaptophenyl methyl sulfone 
• 60036-47-7 o-methylsulphonylphenyl methyl sulphide 
• 19111-44-5 α--phenylessigsaeure 

Relevant articles and documents

Hydro/deutero deamination of arylazo sulfones under metal and (photo)catalyst-free conditions

Hydrodeaminated and monodeuterated aromatics were obtained via a visible-light driven reaction of arylazo sulfones. Deuteration occurs efficiently in deuterated media such as isopropanol-d8 or in THF-d8/water mixtures and exhibits a high tolerance to the nature and the position of the aromatic substituents.

Copper-catalyzed aerobic oxidation and cleavage/formation of C-S bond: A novel synthesis of aryl methyl sulfones from aryl halides and DMSO

With atmospheric oxygen as the oxidant, a novel copper(i)-catalyzed synthesis of aryl methyl sulfones from aryl halides and widely available DMSO is described. The procedure tolerates aryl halides with various functional groups (such as methoxy, acetyl, chloro, fluoro and nitro groups), which could afford aryl methyl sulfones in moderate to high yields. The copper-catalyzed aerobic oxidation and the cleavage/formation of C-S bond are the key steps for this transformation.

Anion-functionalized ionic liquids enhance the cui-catalyzed cross-coupling reaction of sulfinic acid salts with aryl halides and vinyl bromides

An easily accessible, anion-functionalized ionic liquid, 1-ethyl-3-methylimidazolium (S)-2-amino-3-methylbutyric acid salt, [emim][Val], has been demonstrated to be an efficient additive for the CuI-catalyzed coupling reaction of sulfinic acid salts with aryl iodides, aryl bromides and vinyl bromides, leading to the formation of sulfones in good yields. Georg Thieme Verlag Stuttgart.