29909-72-6

Basic information

• Product Name: 3-PHENYLBENZOFURAN
• Synonyms: 3-PHENYLBENZOFURAN
• CAS NO: 29909-72-6
• Molecular Formula: C₁₄H₁₀O
• Molecular Weight: 194.23
• Mol File: 29909-72-6.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 325.1°C at 760 mmHg
• Flash Point: 158.4°C
• Appearance: /
• Density: 1.131g/cm³
• Vapor Pressure: 0.000447mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 3-PHENYLBENZOFURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYLBENZOFURAN(29909-72-6)
• EPA Substance Registry System: 3-PHENYLBENZOFURAN(29909-72-6)

Safety Data

• Hazardous Substances Data: 29909-72-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H10O/c1-2-6-11(7-3-1)13-10-15-14-9-5-4-8-12(13)14/h1-10H

Upstream product

• 271-89-6 1-benzofurane 
• 71-43-2 benzene 
• 39477-86-6 1-phenyl-1-(2-hydroxyphenyl)ethene 
• 70-11-1 α-bromoacetophenone 
• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 16002-63-4 phenylmagnesium iodide 
• 59214-70-9 3-bromobenzofuran 
• 42434-88-8 2-(2-bromophenoxy)-1-phenyl-1-ethanone 
• 858855-11-5 5-bromo-2-iodo-phenol 
• 207115-22-8 4-bromo-2-iodophenol 
• 533-58-4 2-Iodophenol 
• 95-56-7 2-hydroxybromobenzene 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 721-04-0 2-phenoxy-1-phenylethanone 

Downstream Products

• 111864-84-7 trans-2-methoxy-3-phenyl-2,3-dihydrobenzofuran 
• 111864-84-7 cis-2-methoxy-3-phenyl-2,3-dihydrobenzofuran 
• 60312-24-5 PL-158 
• 98054-95-6 trans-4-methyl-2-(2'-(3'-phenyl)benzofuranyl)-N-trifluoroacetyl piperidine 
• 98035-92-8 2,2,2-Trifluoro-N-[3-methyl-5,5-bis-(3-phenyl-benzofuran-2-yl)-pentyl]-acetamide 
• 28089-84-1 2-acetyl-3-phenylbenzofuran 
• 96336-19-5 2-nitro-3-phenyl-benzofuran 
• 1839-72-1 2-phenylbenzofuran 

Relevant articles and documents

Electro-Oxidative C-N Bond Formation through Azolation of Indole Derivatives: An Access to 3-Substituent-2-(Azol-1-yl)indoles

A practical protocol to synthesize 3-substituent-2-(azol-1-yl)indole derivatives has been developed via an electrochemical oxidative cross coupling process under mild conditions. This electro-oxidative C-N bond formation strategy tolerates a range of functional groups and is amenable to gram scale synthesis. Moreover, this method was applied to the late-stage functionalization of bioactive molecules.

Acid-promoted selective synthesis of trifluoromethylselenolated benzofurans with Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate

A Br?nsted acid-promoted trifluoromethylselenolation of benzofurans was disclosed by using Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate as a stable and easily prepared electrophilic trifluoromethylselenolating reagent. A wide range of SeCF3-substituted benzofuran derivatives were obtained in moderate to good yields with excellent regioselectivity. The tandem cyclization/trifluoromethylselenolation procedure of 1-methoxy-2-(arylethynyl)benzenes were also realized by engaging FeCl3 as the catalyst.

Sequential One-Pot Synthesis of 3-Arylbenzofurans from N-Tosylhydrazones and Bromophenol Derivatives

A divergent and efficient one-pot sequence allowing direct access to 3-arylbenzofuran derivatives has been developed. The process, involving N-tosylhydrazones and bromophenols, proceeds via a palladium-catalyzed Barluenga-Valdés cross-coupling, followed by an aerobic, copper-catalyzed, radical cyclization to form Csp2-Csp2 and O-Csp2 bonds. 3-Arylated benzofurans bearing various substituents were obtained with good to excellent yields (up to 90%). Mechanistic investigation strongly supports a radical process for the cyclization step.