299464-98-5

Upstream product

• 110691-01-5 6-amino-4-(4-methoxyphenyl)-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitrile 
• 79-07-2 Chloroacetamide 
• 309268-54-0 6-amino-2-[(carboxamidomethyl)thio]-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile 
• 102423-74-5 2,6-diamino-4-(4-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant academic research and scientific papers

Multicomponent Synthesis of 4-Alkyl(Aryl, Hetaryl)-2-alkoxycarbonyl(aroyl, carbamoyl)- 3,6-diamino-5-cyanothieno[2,3-b]pyridines

The condensation of malononitrile with hydrogen sulfide and aldehydes in the presence of triethylamine in ethanol at room temperature afforded 4-alkyl(aryl, hetaryl)-2,6-diamino-3,5-dicyano-4H-thiopyrans. Treatment of the latter in situ with alkali in DMF, followed by addition of an alkylating agent, led to the formation of 4-alkyl(aryl, hetaryl)-2-alkoxycarbonyl(aroyl, carbamoyl)-3,6-diamino-5-cyanothieno[2,3-b]- pyridines.

Keactions with 3,6-diaminothieno[2,3-b]-pyridines: Synthesis and characterization of several new fused pyridine heterocycles

6-Aminopyridine-2(1H)thiones 1 reacting with a-halo-compounds 2a-c afforded the alkylthiopyridine derivatives 3a-c which in turn cyclized to the corresponding thieno[2,3-b]pyridine derivatives 4a-c. Several thieno[2,3-b]pyridine derivatives 7, 16, 19, pyr