299964-43-5 Usage
Uses
Used in Pharmaceutical Industry:
(1R)-3-[3-amino-4-(benzyloxy)phenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethan-1-ol is used as a potential drug candidate for its ability to engage with biological systems, which may offer therapeutic benefits. (1R)-3-[3-amino-4-(benzyloxy)phenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethan-1-ol's unique structure and functional groups could allow it to target specific biological pathways or receptors, contributing to the development of new treatments for various diseases.
Further research is necessary to determine the specific applications of (1R)-3-[3-amino-4-(benzyloxy)phenyl]-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethan-1-ol within the pharmaceutical industry, including its potential role in the treatment of specific conditions or its use in drug delivery systems to enhance bioavailability and therapeutic efficacy. As with any new drug candidate, extensive testing and clinical trials are required to establish safety, efficacy, and optimal dosages before it can be considered for widespread use in medical treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 299964-43-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,9,9,6 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 299964-43:
(8*2)+(7*9)+(6*9)+(5*9)+(4*6)+(3*4)+(2*4)+(1*3)=225
225 % 10 = 5
So 299964-43-5 is a valid CAS Registry Number.
299964-43-5Relevant articles and documents
An efficient enantioselective synthesis of (R,R)-formoterol, a potent bronchodilator, using lipases
Campos, Francisco,Bosch, M. Pilar,Guerrero, Angel
, p. 2705 - 2717 (2007/10/03)
The potent β2-adrenergic receptor agonist formoterol (R,R)-1 has been obtained in enantiomerically pure form by a convenient chemoenzymatic approach by coupling of epoxide (R)-6 with the unprotected primary amine (R)-9. Both chiral precursors have been prepared by enantiodifferentiation processes involving Pseudomonas cepacia (lipase PS) and Candida antarctica lipase (CALB), respectively. For the resolution of amine 9, we have found that utilization of triethylamine as non-reactive base enhances the reaction rate and the enantioselectivity of the process. The key coupling reaction of (R)-6 and (R)-9 has been conducted through derivatization of the amine with the labile trimethylsilyl group, which liberates the amino group of the resulting amino alcohol (R,R)-11 upon column chromatography purification. In this way, the overall approach is shorter than others previously described. Copyright (C) 2000 Elsevier Science Ltd.
