3005-87-6

Basic information

• Product Name: Cbz-Gly-Gly-OEt
• Synonyms: Cbz-Gly-Gly-OEt;N-(Benzyloxycarbonyl)glycylglycine ethyl ester;N-[N-(Benzyloxycarbonyl)glycyl]glycine ethyl ester
• CAS NO: 3005-87-6
• Molecular Formula: C₁₄H₁₈N₂O₅
• Molecular Weight: 294.3
• Mol File: 3005-87-6.mol
• Article Data: 32

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cbz-Gly-Gly-OEt(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-Gly-Gly-OEt(3005-87-6)
• EPA Substance Registry System: Cbz-Gly-Gly-OEt(3005-87-6)

Safety Data

• Hazardous Substances Data: 3005-87-6(Hazardous Substances Data)

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 459-73-4 GlyOEt*HCl 
• 2949-22-6 Glycine ethyl ester isocyanate 
• 1499-17-8 o-phenylene chlorophosphate 
• 2899-60-7 Cbz-Gly-ONSuc 
• 25084-56-4 Coc-Gly-OEt 
• 637-81-0 ethyl-2-azidoacetate 
• 623-33-6 glycine ethyl ester hydrochloride 
• 100-74-3 N-ethylmorpholine; 
• 71760-04-8 propylphosphonic anhydride 
• 814-49-3 diethyl chlorophosphate 
• 1280225-75-3 C₂₀H₂₄N₂O₆ 
• 501-53-1 benzyl chloroformate 
• 87023-85-6 1-(Cbz-glycyl)-3,5-dimethylpyrazole 

Downstream Products

• 2566-19-0 CbzGlyGly 
• 3252-83-3 Cbz-glycylglycyl hydrazide 
• 6422-35-1 Z-glycylglycinamide 
• 20980-94-3 Z-Gly-ψ(CSNH)-Gly-OEt 
• 41445-96-9 Z-Gly-Gly-N₃ 
• 859307-62-3 N-benzyloxycarbonyl-glycyl=>glycyl=>glycine phenyl ester 
• 2503-35-7 N-benzyloxycarbonyl-glycyl=>glycyl=>-glycine ethyl ester 
• 2566-20-3 [2-(2-Benzyloxycarbonylamino-acetylamino)-acetylamino]-acetic acid 
• 4811-37-4 N-benzyloxycarbonyl-glycyl=>glycyl=>glycyl=>-glycine ethyl ester 
• 107941-81-1 N-(benzyloxycarbonyl)-O-tert-butyltyrosylglycylglycine ethyl ester 
• 95750-15-5 Z-Gly-ψ(CSNH)-Gly 
• 93726-38-6 1-(Cbz-glycylglycyl)-3,5-dimethylpyrazole 
• 96943-01-0 N,N'-bis(carboxymethyl)urea 
• 66179-54-2 N-Benzyloxycarbonyl-glycyl-glycyl-hydroxamsaeure 

Relevant articles and documents

Metalloporphyrin receptors for histidine-containing peptides

Two new ditopic metalloporphyrin receptors constructed by combining metalloporphyrin with crown ethers have been prepared and characterized. 1H NMR and MS spectra confirmed the complexation of receptor with peptide driven by coordination interaction and hydrogen bonding. UV/vis experiments revealed that the receptors exhibited high binding affinity to histidine-containing peptides. These receptors could differentiate short peptides of C-terminal histidine and N-terminal histidine and formed the most stable complexes with tripeptide.

Bromelain catalyzed synthesis of peptides in organic solvent

For the first time, immobilized bromelain was shown to maintain high catalytic activity in organic solvent and to form peptide bonds. It requires only 7 hours to obtain Cbz-Gly-L-Leu-OMe in 85% yield. The precursor of aspartame (Cbz-L-Asp-L-Phe-OMe) and other dipeptides were also synthesized by this method.