303110-96-5Relevant academic research and scientific papers
PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES
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Page/Page column 12; 21, (2008/06/13)
The preparation of an intermediate, a process for the preparation thereof and the process of preparing [4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-2-methyl-phenoxy]-acetic acid using this intermediate are described.
Identification and synthesis of a novel selective partial PPARδ agonist with full efficacy on lipid metabolism in vitro and in vivo
Sauerberg, Per,Olsen, Grith S.,Jeppesen, Lone,Mogensen, John P.,Pettersson, Ingrid,Jeppesen, Claus B.,Daugaard, Jens R.,Galsgaard, Elisabeth D.,Ynddal, Lars,Fleckner, Jan,Panajotova, Vladimira,Polivka, Zdenek,Pihera, Pavel,Havranek, Miroslav,Wulff, Erik M.
, p. 1495 - 1503 (2008/02/03)
The aim was to identify a novel selective PPARδ agonist with full efficacy on free fatty acid (FFA) oxidation in vitro and plasma lipid correction in vivo. Using the triple PPARα,γ,δ agonist 1 as the structural starting point, we wanted to investigate the
Novel compounds, their preparation and use
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Page/Page column 26; 27, (2010/02/11)
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be u
Novel compounds, their preparation and use
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Page/Page column 18, (2010/02/11)
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be u
NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR THERAPEUTICAL USE
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Page 40, (2010/02/06)
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may b
NOVEL COMPOUNDS, THEIR PREPARATION AND USE
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Page 50, (2010/02/06)
Novel compounds of the general formula (I), the use of these compounds as pharma-ceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be
Novel compounds, their preparation and use
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Page/Page column 20, (2010/02/07)
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be u
NOVEL COMPOUNDS USEFUL IN TREATING PPAR MEDIATED DISEASES
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Page 38, (2010/11/30)
Novel compounds of the general formula (I), the use of these compounds as pharma-ceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be
Design and synthesis of novel PPARα/γ/δ triple activators using a known PPARα/γ dual activator as structural template
Mogensen, John P.,Jeppesen, Lone,Bury, Paul S.,Pettersson, Ingrid,Fleckner, Jan,Nehlin, Jan,Frederiksen, Klaus S.,Albrektsen, Tatjana,Din, Nanni,Mortensen, Steen B.,Svensson, L. Anders,Wassermann, Karsten,Wulff, Erik M.,Ynddal, Lars,Sauerberg, Per
, p. 257 - 260 (2007/10/03)
Using a known dual PPARα/γ activator (5) as a structural template, SAR evaluations led to the identification of triple PPARα/γ/δ activators (18-20) with equal potency and efficacy on all three receptors. These compounds could become useful tools for studying the combined biological effects of PPARα/γ/δ activation.
Novel compounds, their preparation and use
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, (2008/06/13)
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be u
