494865-12-2Relevant academic research and scientific papers
Identification and synthesis of a novel selective partial PPARδ agonist with full efficacy on lipid metabolism in vitro and in vivo
Sauerberg, Per,Olsen, Grith S.,Jeppesen, Lone,Mogensen, John P.,Pettersson, Ingrid,Jeppesen, Claus B.,Daugaard, Jens R.,Galsgaard, Elisabeth D.,Ynddal, Lars,Fleckner, Jan,Panajotova, Vladimira,Polivka, Zdenek,Pihera, Pavel,Havranek, Miroslav,Wulff, Erik M.
, p. 1495 - 1503 (2008/02/03)
The aim was to identify a novel selective PPARδ agonist with full efficacy on free fatty acid (FFA) oxidation in vitro and plasma lipid correction in vivo. Using the triple PPARα,γ,δ agonist 1 as the structural starting point, we wanted to investigate the
