30364-58-0

Basic information

• Product Name: 2,5-Pyrrolidinedione, 1-[(4-nitrobenzoyl)oxy]-
• CAS NO: 30364-58-0
• Molecular Formula: C11H8N2O6
• Molecular Weight: 264.194
• Mol File: 30364-58-0.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 1-[(4-nitrobenzoyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 1-[(4-nitrobenzoyl)oxy]-(30364-58-0)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 1-[(4-nitrobenzoyl)oxy]-(30364-58-0)

Safety Data

• Hazardous Substances Data: 30364-58-0(Hazardous Substances Data)

Usage

Appearance

Bright yellow dye.

Usage

Commonly used as a pH indicator in laboratory experiments.

Chemical Structure

Contains a pyrrolidinedione ring with a nitrobenzoyloxy group attached to one of the nitrogen atoms.

Solubility

Soluble in water.

Applications

Used in biochemistry and molecular biology applications to detect pH changes in reaction mixtures and as a colorimetric reagent for the determination of zirconium and thorium in aqueous solutions.

Stability

Considered to be stable under normal conditions but should be handled and stored in a manner consistent with good laboratory practices.

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 122-04-3 4-nitro-benzoyl chloride 
• 555-16-8 4-nitrobenzaldehdye 
• 636-98-6 p-nitrobenzene iodide 
• 17592-54-0 2,5-dioxopyrrolidin-1-yl formate 
• 619-73-8 4-nitrobenzyl chloride 
• 201230-82-2 carbon monoxide 
• 62-23-7 4-nitro-benzoic acid 

Downstream Products

• 76806-96-7 N-(N'-Ethyl-2-aminoethyl)-p-nitrobenzamide 
• 7506-46-9 N-cyclohexyl-4-nitrobenzamide 
• 1613-76-9 4-nitrobenzohydroxamic acid 
• 62497-65-8 4-nitro-N-phenethylbenzamide 
• 53578-11-3 (4-nitrophenyl)(pyrrolidin-1-yl)methanone 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 3460-11-5 4-nitrobenzanilide 

Relevant articles and documents

N -Heterocyclic carbene (NHC) catalyzed amidation of aldehydes with amines via the tandem N -hydroxysuccinimide ester formation

A facile method for the amidation of aldehydes by a cascade approach was developed. This methodology, reported for the first time, uses a N-heterocyclic carbene (NHC) as the catalyst, and N-hydroxysuccinimide (NHS) mediated synthesis of amides utilising TBHP as the oxidant. Various substituted aldehydes reacted smoothly with NHS giving the corresponding active esters in moderate to good yields, which facilely converted into amides in one pot. In addition, the drug moclobemide was synthesized to represent the practical utility of the developed methodology. This journal is

Iron-Nitrate-Catalyzed Oxidative Esterification of Aldehydes and Alcohols with N-Hydroxyphthalimide: Efficient Synthesis of N-Hydroxyimide Esters

An Fe(NO3)3·9H2O-catalyzed cross-dehydrogenative coupling reaction between N-hydroxyphthalimide (NHPI) or N-hydroxysuccinimide (NHSI) and aldehydes or alcohols in air is described. This transformation represents an efficient approach to the preparation of N-hydroxyimide ester derivatives in moderate to excellent yields, and has a wide substrate scope.

Cross dehydrogenative coupling (CDC) of aldehydes with N-hydroxyimides by visible light photoredox catalysis

A photoinduced cross-dehydrogenative-coupling (CDC) reaction between aldehydes and N-hydroxyimides has been developed for the synthesis of ester derivatives. Using 2 mol% [Ru(bpy)3]Cl2 in dry acetonitrile at room temperature with an LED light bulb, we were able to synthesize N-hydroxyesters in good yields. The ester derivatives are very useful synthetic intermediates, which were transformed to amide and oxazole building blocks in excellent yields. This journal is