30412-42-1

Basic information

• Product Name: 3-(bromomethyl)-2-fluoropyridine
• Synonyms: 3-(bromomethyl)-2-fluoropyridine
• CAS NO: 30412-42-1
• Molecular Formula: C₆H₅BrFN
• Molecular Weight: 190.0130032
• Mol File: 30412-42-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 3-(bromomethyl)-2-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(bromomethyl)-2-fluoropyridine(30412-42-1)
• EPA Substance Registry System: 3-(bromomethyl)-2-fluoropyridine(30412-42-1)

Safety Data

• Hazardous Substances Data: 30412-42-1(Hazardous Substances Data)

Usage

General Description

3-(bromomethyl)-2-fluoropyridine is a chemical compound with the molecular formula C6H5BrFN. It is a pyridine derivative with a bromomethyl group attached at the 3-position and a fluorine atom at the 2-position of the pyridine ring. 3-(bromomethyl)-2-fluoropyridine is commonly used as a building block in organic synthesis and pharmaceutical research. It is known for its reactivity in various chemical reactions, including cross-coupling reactions and nucleophilic substitution reactions. The presence of the bromomethyl and fluorine groups makes 3-(bromomethyl)-2-fluoropyridine a valuable intermediate for the production of various functionalized pyridine derivatives and heterocyclic compounds with diverse applications in the pharmaceutical and agrochemical industries.

Upstream product

• 131747-55-2 2-fluoro-3-(hydroxymethyl)pyridine 
• 2369-18-8 2-fluoro-3-methylpyridine 

Downstream Products

• 1314887-05-2 (S)-3-(2-fluoropyridin-3-yl)-2-phenylpropanoic acid 

Relevant articles and documents

In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain

Monoamine oxidases (MAOs) play a key role in the metabolism of major monoamine neurotransmitters. In particular, the upregulation of MAO-B in Parkinson's disease, Alzheimer's disease and cancer augmented the development of selective MAO-B inhibitors for d

NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME

The present invention relates to a pyrrolopyridine derivative represented by the Chemical Formula I, and a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and relates to an antiviral composition including the same as an active ingredient. The compound of the Chemical Formula I has excellent antiviral activity and selectivity for wild type and resistant HIV-1, and thereby is useful as a therapeutic agent for acquired immune deficiency syndrome (AIDS).

3 -AMINO- PYRAZOLE DERIVATIVES USEFUL AGAINST TUBERCULOSIS

A compound of Formula (I) or a pharmaceutically acceptable salt thereof: Wherein: Het is a 5 to 10-membered heteroaromatic ring; Either X is N and Y is CR5; or X is C and Y is S; Z is selected from N and CH; R1 is selected from H and C1-2alkyl; R2 is selected from H, C1-2alkyl, OH, —CH2OH and C1-2alkoxy; Each R3 is independently selected from OH, C1-3alkyl, F, Cl, Br, NH2, and C1-3alkoxy; R4 is selected from C1-3alkyl and haloC1-3alkyl; R5 is selected from H, C1-3alkyl and haloC1-3alkyl; R6 and R7 are either i) each independently selected from H, C1-3alkyl and C1-3alkoxy; or ii) R6 and R7 together with the ring to which they are attached form a 9-membered bicyclic ring; p is 0-3; and RA is selected from H and C1-3alkyl, compositions containing them, their use in therapy, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.