304460-23-9Relevant academic research and scientific papers
Development of a CuCl/phosphine system to catalyze phenylation and methylation of N-tosyl aldimines with phenylboronic andmethylboronic acids
Ashouri, Akram,Nasiri, Behzad,Pourian, Somayeh,Samadi, Saadi,Zamani, Hossein
, p. 575 - 581 (2021/01/13)
The addition of phenylboronic and methylboronic acids to activated aromatic aldimines was demonstrated in the presence of copper(I)-phosphine complexes. The desired products were obtained using copper chloride/phosphine, and potassium fluoride in under toluene reflux, in moderate-to-good yield and a suitable reaction time.
Alkylation of Sulfonamides with Trichloroacetimidates under Thermal Conditions
Wallach, Daniel R.,Chisholm, John D.
, p. 8035 - 8042 (2016/09/12)
An intermolecular alkylation of sulfonamides with trichloroacetimidates is reported. This transformation does not require an exogenous acid, base, or transition metal catalyst; instead the addition occurs in refluxing toluene without additives. The sulfonamide alkylation partner appears to be only limited by sterics, with unsubstituted sulfonamides providing better yields than more encumbered N-alkyl sulfonamides. The trichloroacetimidate alkylating agent must be a stable cation precursor for the substitution reaction to proceed under these conditions.
Cobalt-catalyzed intermolecular C-H amination with bromamine-T as nitrene source
Harden, Jeremiah D.,Ruppel, Joshua V.,Gao, Guang-Yao,Zhang, X. Peter
, p. 4644 - 4646 (2008/09/21)
Cobalt, supported by porphyrin ligands, is capable of catalyzing intermolecular nitrene insertion of sp3 C-H bonds with bromamine-T as the nitrene source, forming the desired tosyl-protected amines with NaBr as the by-product. The Royal Society
